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Tanzi R. on PAPER: Gandy S. et al., 2012, Given what Lee Goldstein, Ann McKee, and colleagues observed in the brains of blast victims and... 18 May 2012.
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Tanzi R. on NEWS: Large Genetic Analysis Pays Off With New AD Risk Genes, The two new Alzheimer's GWAS reports from the NIA-ADGC (Naj et al., 2011) and European... 5 Apr 2011.
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Tanzi R. on NEWS: More AD Genetics—A Familial Hit from the ADAMs Family, To further clarify, the two mutations were present in seven out of ~1300 AD families screened.... 15 Aug 2009.
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Tanzi R. on PAPER: Britschgi M. et al., 2009, The Britshgi et al. paper nicely confirms our 2005 study (Moir et al., 2005) in which we... 14 Jul 2009.
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Moir R, Tanzi R. on PAPER: Soscia SJ. et al., 2010, Reply to Anonymous by Rob Moir and Rudy Tanzi
Our identification of Aβ as an... 20 Apr 2009.
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Tanzi R. on NEWS: Scouting AD’s “Little League” Genes: Can Systems Biology Help?, Regarding the value of identifying all of the minor genetic risk factors for AD and the role of... 22 May 2008.
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Li A, Tanzi R. on PAPER: Ganguly A. et al., 2008, Drosophila Studies Reveal the Functional Roles of Ubiquilin 1 in Alzheimer... 30 Oct 2007.
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Tanzi R. on LIVE DISCUSSION: Presenilin Loss of Function—Plan B for AD?, In the field of genetics, it is a rare and precious opportunity that we are afforded as... 20 Feb 2007.
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Tanzi R. on NEWS: SORLA Soars—Large Study Links Gene to Late-onset AD, Update: With regard to my earlier comment on the SORL1-AD genetic association study by Rogaeva... 15 Jan 2007.
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Tanzi R. on NEWS: SORLA Soars—Large Study Links Gene to Late-onset AD, This new study showing association of SORL1 with late-onset Alzheimer disease (LOAD) provides... 15 Jan 2007.
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Tanzi R. on PAPER: Larner AJ. et al., 2007, We first described the PSEN1-R269H mutation in a single case of early-onset AD (Gomez-Isla et... 8 Jan 2007.
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Tanzi R. on LIVE DISCUSSION: Gain or Loss of Function—Time to Shake up Assumptions on γ-Secretase in Alzheimer Disease?, In response to Dr. Pimplikar: With regard to effects of the presenilin 2 (PS2)-N141I FAD... 13 Jun 2006.
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Tanzi R. on LIVE DISCUSSION: Gain or Loss of Function—Time to Shake up Assumptions on γ-Secretase in Alzheimer Disease?, Human genetics clearly informs us that more than 150 FAD mutations in APP and the presenilins... 30 May 2006.
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Tanzi R. on LIVE DISCUSSION: Gain or Loss of Function—Time to Shake up Assumptions on γ-Secretase in Alzheimer Disease?, From a genetic standpoint, the fact that presenilin and APP mutations are autosomal dominant... 2 May 2006.
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Bush A, Tanzi R. on NEWS: Side-Reactions Sideswipe Clioquinol—Prevent Clinical Trial, Prana's decision to cancel the phase II/III "PLACQUE" clinical trial of PBT1 is, of course,... 14 Apr 2005.
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Tanzi R. on NEWS: An AD Gene Nugget on Chromosome 12?, For a chromosome (chr 12) with only marginal genetic linkage signals, an unexpectedly large... 20 Oct 2004.
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Tanzi R. on SITE POLL: Does gamma-secretase remain an attractive therapeutic target?, The missing choice in this poll is to block gamma-secretase allosterically to preferentially... 12 Oct 2004.
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Tanzi R. on NEWS: ABCA1 Links Cholesterol and ApoE, But It May Not Be a Risk Factor for AD, After ApoE, which has an unusually large effect size as a
late-onset AD gene, the remaining AD... 13 Aug 2004.
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Bertram L, Tanzi R. on PAPER: Li YJ. et al., 2003, In a follow-up to their recent study reporting a locus that influences age-at-onset in... 26 Nov 2003.
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Tanzi R. on PAPER: Myers A. et al., 2000, Recommendation Only. 11 Jul 2003.
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Tanzi R. on PAPER: Ertekin-Taner N. et al., 2000, Recommendation Only. 11 Jul 2003.
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Tanzi R. on PAPER: Bertram L. et al., 2000, Recommendation Only. 11 Jul 2003.
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Tanzi R. on PAPER: Abraham R. et al., 2001, Regarding John Hardy's quote at the recent German AD meeting (reported on by Kahle and... 13 Apr 2003.
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Tanzi R, Tesco G. on PAPER: Soriano S. et al., 2001, Seminal studies of LeBlanc (1995) have shown that primary neurons committed to undergo apoptosis... 29 Jun 2002.
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Tanzi R. on NEWS: Single Gene May Influence Onset of Both Alzheimer's and Parkinson's, The new genome screen on Alzheimer's and Parkinson's diseases reported by Pericak-Vance et al.... 15 Mar 2002.
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Tanzi R. on NEWS: The A2M Deletion, Revisited, Response from Rudy Tanzi
In Peter Hyslop's reply to the Alzheimer Forum News article on "A2M... 6 May 1999.
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Tanzi R. on NEWS: The A2M Deletion, Revisited, Thanks for summarizing the three new A2M genetics papers and our reply
in Nature Genetics (May... 6 May 1999.
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Tanzi R. on LIVE DISCUSSION: In Search of γ-Secretase, Reply to Ratan Bhat by Rudy Tanzi:
The main problem with this hypothesis is that... 26 Apr 1999.
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Tanzi R. on NEWS: Sixth Int. Conference on AD: Genetics I, As a quick comment regarding Luc Buee's summary of Dr. Lindsay Farrer's talk on the genetics of... 7 Aug 1998.
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Tanzi R. on NEWS: Sixth Int. Conference on AD: Search for Late-Onset AD Genes, Dr. Lukiw does not mention that Dr. Peggy Vance reported that she replicated our significant... 7 Aug 1998.
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