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1 to 24 of 24 results |
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Takashima A. on NEWS: Tau’s Synaptic Hats: Regulating Activity, Disrupting Communication, In this manuscript, Hoover and colleagues report that overexpressed tau distributes to dendritic... 20 Jan 2011.
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Takashima A. on PAPER: Zempel H. et al., 2010, This manuscript is very interesting. Mandelkow’s group basically has studied many aspects of... 16 Sep 2010.
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Takashima A. on NEWS: Honolulu: The Missing Link? Tau Mediates Aβ Toxicity at Synapse, In this manuscript, Ittner and colleagues showed that tau has a role in Aβ toxicity, which may... 26 Jul 2010.
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Takashima A. on PAPER: Tackenberg C. et al., 2009, Tackenberg and Brandt showed that Aβ is involved in synapse loss, and that hyperphosphorylated... 11 Dec 2009.
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Takashima A. on PAPER: Basi GS. et al., 2010, Recommendation Only. 1 Dec 2009.
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Takashima A. on PAPER: Abramov E. et al., 2009, This is quite an interesting paper. Abramov and colleagues carefully investigated the role of Aβ... 1 Dec 2009.
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Takashima A. on PAPER: Nicolia V. et al., 2009, Recommendation Only. 25 Nov 2009.
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Takashima A. on PAPER: Dickson DW. et al., 2009, Recommendation Only. 25 Nov 2009.
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Takashima A. on PAPER: Lapointe NE. et al., 2009, This is a very interesting paper. It indicates that a new tau isoform, other than the... 25 Nov 2009.
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Sahara N, Takashima A. on PAPER: Wang Y. et al., 2009, In this manuscript, Yipeng Wang and colleagues showed lysosome/macroautophagy as a new tau... 28 Aug 2009.
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Takashima A. on NEWS: Axonal Transport Not Bothered by Tau Elevation In Vivo, In this paper, Randy Nixon’s group first demonstrated in vivo that axonal transport rates are... 14 Feb 2008.
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Takashima A. on NEWS: Mitochondrial Gridlock—Syntaphilin Puts Brakes on Axonal Transport, We know, based on Mandelkow’s and Hirokawa’s work, that accumulation of tau in neurons inhibits... 23 Jan 2008.
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Takashima A. on PAPER: Luo W. et al., 2007, In this paper, Luo and colleagues showed that PU24FCI inhibited Hsp90 activity and accelerated... 30 May 2007.
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Takashima A. on LIVE DISCUSSION: Presenilin Loss of Function—Plan B for AD?, How Might Presenilin-1 (PS1) Mutations Induce Early-onset Alzheimer Disease?
Shen... 2 Mar 2007.
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Takashima A. on PAPER: King ME. et al., 2006, King and colleagues expanded on a previous report by Rapport and colleagues that showed that tau... 6 Dec 2006.
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Takashima A. on NEWS: Mutant Tau Sharpens Wits of Young Mice, Boekhoorn and colleagues indicated that their P301L tau transgenic mice showed higher LTP and... 14 Apr 2006.
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Takashima A. on PAPER: Kitazawa M. et al., 2005, Epidemiological studies indicate that populations taking anti-inflammatory drugs have a... 10 Oct 2005.
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Takashima A. on NEWS: No Toxicity in Tau’s Tangles?, SantaCruz and colleagues manipulated transgenic tau levels using the tet-off system. Their... 15 Jul 2005.
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Takashima A. on LIVE DISCUSSION: Cell Death: Time to Push It Out of the Doldrums, I read Yong Shen's review on molecular events of neuron death in AD, and the comments, with... 15 Jul 2004.
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Takashima A. on PAPER: Feng R. et al., 2004, By Akihiko Takashima
In this paper, Feng and colleagues showed that neurodegeneration occurred... 24 May 2004.
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Takashima A. on NEWS: GSK3β—Not Just for Tauists Anymore, This report on a connection between AKT-GSK3β signaling and schizophrenia provides evidence... 30 Jan 2004.
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Takashima A. on NEWS: Aiding and Abetting, Hyperactive CDK5 Gives Mouse Tangles, Tau aggregation is a central issue for understanding tauopathies, including AD. Crossbreeding... 27 May 2003.
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Takashima A. on NEWS: Lithium Hinders Aβ Generation, Buffing Up GSK as Drug Target, It was with surprise that I read these results about the role of LiCl in GSK3 inhibition that... 27 May 2003.
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Takashima A. on NEWS: Transgenic Mice Accumulate Human Tau in Degenerating Hippocampal Neurons, Reply by Akihiko Takashima
Regarding Peter Davies' comment, I would like to reply. We... 7 Jan 2002.
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1 to 24 of 24 results |
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The ALS Forum is a web-based collaborative effort to bring together valuable ALS-related resources for use by researchers worldwide in both academia and industry-based settings.
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Should the FDA be allowed to use data from overseas clinical trials? |
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Absolutely, we are running out of viable subjects in the U.S. |
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 9 |
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Yes, so long as the data is reliable |
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31 |
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No, the trials are not as rigorous |
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3 |
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No, the data should be repeated in the U.S. |
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5 |
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No, the drug sponsors are just trying to cut corners |
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3 |
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Responses: 51 |
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Archived Polls |
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