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1 to 21 of 21 results |
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Selkoe D. on NEWS: New Assays for Aβ Oligomers—Spinal Fluid a Miss, Brain Awash, Regarding the comment about SDS-PAGE potentially inducing artifactual dimers from the natural Aβ... 6 Feb 2013.
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Selkoe D. on NEWS: CTAD: New Data on Sola, Bapi, Spark Theragnostics Debate, Dr. Imbimbo’s perspective has been voiced before by a minority of AD investigators who believe... 26 Nov 2012.
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Selkoe D. on NEWS: CTAD: New Data on Sola, Bapi, Spark Theragnostics Debate, CTAD provided excitement, important insights, and new questions, as would be expected for a... 12 Nov 2012.
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Bartels T, Dettmer U, Luth E, Selkoe D. on PAPER: Fauvet B. et al., 2012, Since our publication (Bartels et al., 2011), we have conducted extensive experiments using both... 10 Feb 2012.
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Selkoe D. on PAPER: Selkoe DJ. et al., 2011, Dr. Smith makes good points. I concur that some potentially disease-modifying trials (such as... 5 Oct 2011.
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Bartels T, Selkoe D. on PAPER: Bartels T. et al., 2011, We thank Julia George and Torleif Hard for their helpful comments and agree with both... 25 Aug 2011.
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Selkoe D. on NEWS: An α-Synuclein Twist—Native Protein a Helical Tetramer, Reply to comments by Eliezer Masliah and Hilal Lashuel
Comments by Dr. Lashuel... 22 Aug 2011.
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Selkoe D. on NEWS: Amyloid-Blocking Drug Poised for Approval for Rare Disease, I am familiar with the tafamidis work and the recent recommendation of its approval for FAP. I... 19 Aug 2011.
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Selkoe D. on PAPER: Winton MJ. et al., 2011, In my view, the paper by Winton et al. supports the key point that one can prove the
existence... 13 Jun 2011.
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Selkoe D. on PAPER: Golde TE. et al., 2011, Golde et al. have done a real service to the field of Alzheimer's disease therapeutics by... 31 Jan 2011.
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Selkoe D. on NEWS: The Toxic Fold? Aβ Dodecamers, Tetramers Show Their Conformations, I am concerned about drawing firm conclusions about what
happens in the human brain from pure... 17 Jun 2009.
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Selkoe D, Townsend M. on NEWS: How Does Aβ Do Harm? New Clues on Insulin Signaling, Spines, Inflammation, Comment by Matt Townsend and Dennis Selkoe
In response to Sanjay Pimplikar's... 27 Sep 2007.
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Selkoe D. on NEWS: APP Double Dose Causes Early-Onset AD, This is a very exciting development that strongly supports the amyloid hypothesis of AD... 20 Dec 2005.
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Selkoe D. on PAPER: Marchesi VT. et al., 2005, In his PNAS Perspective, Vincent Marchesi, in characteristic fashion, provides us with... 28 Sep 2005.
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Selkoe D. on LIVE DISCUSSION: Messing with the Membrane—An Alternative Interpretation of the Amyloid-β Hypothesis, In his PNAS Perspective, Vincent Marchesi, in characteristic fashion, provides us with... 28 Sep 2005.
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Selkoe D, Wolfe M, Xia W. on PAPER: Netzer WJ. et al., 2003, The findings of Netzer and colleagues that Gleevec and related protein kinase inhibitors can... 9 Oct 2003.
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Selkoe D. on NEWS: Earliest Amyloid Aggregates Fingered As Culprits, Disrupt Synapse Function in Rats, Our study identifies a specific form of naturally produced human amyloid beta protein, namely... 7 Apr 2002.
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Selkoe D. on NEWS: Conference Coverage: IPSEN Foundation, Dave Holtzman nicely summarizes some of the principal findings of the presenters. In general,... 19 Mar 2002.
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Selkoe D. on NEWS: Insulin-Degrading Enzyme Not, After All, a Risk Factor for AD?, I don't think this paper definitively rules IDE out as a LOAD gene. It
simply says the authors... 1 Feb 2002.
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Selkoe D, Walsh D. on LIVE DISCUSSION: Intracellular Aβ in Alzheimer's Disease, From various studies examining the toxicity of Aβ,
it is clear that random coil monomeric Aβ... 15 May 2000.
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Selkoe D. on LIVE DISCUSSION: In Search of γ-Secretase, Reply by Dennis Selkoe
Dear John:
In response to your News and... 13 Apr 1999.
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1 to 21 of 21 results |
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The ALS Forum is a web-based collaborative effort to bring together valuable ALS-related resources for use by researchers worldwide in both academia and industry-based settings.
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Should the FDA be allowed to use data from overseas clinical trials? |
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Absolutely, we are running out of viable subjects in the U.S. |
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 9 |
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Yes, so long as the data is reliable |
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31 |
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No, the trials are not as rigorous |
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3 |
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No, the data should be repeated in the U.S. |
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5 |
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No, the drug sponsors are just trying to cut corners |
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Responses: 51 |
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