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Reid M. on NEWS: Triplet of Papers Points to Common Gene for Two Syndromes, It's interesting that Ilya Bezprozvanny mentions the known interaction of TRP channels with... 14 Jan 2010.
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Reid M. on NEWS: Chicago: NFATs, Calcineurin—Mediators of AD, PD Pathogenesis?, It's of interest that mRNA levels of the calcineurin inhibitor, DSCR1, are also much higher in... 30 Dec 2009.
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Reid M. on NEWS: NO Joke: Viagra Lessens Aβ, Cognitive Problems in AD Mice, Nitroglycerin is said to easily cross the blood-brain barrier and enhance cGMP expression (1).... 29 Jul 2009.
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Reid M. on PAPER: Soscia SJ. et al., 2010, I have proposed that Aβ may block HPV16 cell entry due to the fact that it depletes dynamin 1. I... 24 Apr 2009.
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Reid M. on PAPER: Park J. et al., 2009, The overexpression DYRK1A and RCAN1, an inhibitor of calcineurin A, are thought to be involved... 7 Apr 2009.
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Reid M. on NEWS: Keystone: Death Receptor Ligand—New Role for APP, New Model for AD?, It's interesting that an androgen receptor coactivator interacts with DR6 and that androgen... 2 Mar 2009.
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Reid M. on NEWS: Aging and Aβ Hit Mitochondria Function, It's interesting that TFAM can prevent age-dependent memory impairment and loss of neuronal... 8 Nov 2008.
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Reid M. on NEWS: Paris: Synaptic Plasticity and the Mechanism of Alzheimer Disease, Jennifer Altman comments on the Sabatini finding that Aβ directly reduces the influx of calcium... 12 Jul 2007.
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Reid M. on NEWS: Stress and AD—Taking a Toll on Tau, Sawchenko reports that tau phosphorylation is abrogated in the absence of CRFR1. Bale and... 3 Jul 2007.
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Reid M. on NEWS: A Growing Problem: Oxidative Damage Drives Trinucleotide Expansions in Aging Brain, Tom Fagan reported in previous research news that enhancing PGC-1α expression may be beneficial... 15 May 2007.
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Reid M. on NEWS: GABA and Plasticity—Can Antagonists Improve Cognition?, It's of interest that Zhao and colleagues (1) found increased efflux of thiamine pyrophosphate... 9 Apr 2007.
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Reid M. on PAPER: Höglinger GU. et al., 2007, It's interesting that the authors report cell cycle-like mechanisms operating in PD brain... 24 Mar 2007.
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Reid M. on NEWS: GABA and Plasticity—Can Antagonists Improve Cognition?, I'd like to put forward the hypothesis that Aβ may compete with pleiotrophin (heparin-binding... 17 Mar 2007.
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Reid M. on PAPER: Tansley GH. et al., 2007, Cheryl Wellington and colleagues report that ABCG1 modulates the subcellular distribution and... 19 Feb 2007.
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Reid M. on NEWS: Aβ—Three Places, Three Ways of Wreaking Havoc, The study by Biswas and colleagues supporting the role of miscreant cell cycle proteins in Aβ... 12 Feb 2007.
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Reid M. on NEWS: Early Intervention Reverses Prion Disease, It would be interesting to see whether PDGF is also able to reverse the disease process if given... 5 Feb 2007.
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Reid M. on NEWS: New Mouse Model Links Mitochondria to Parkinson Disease, It's of interest these signs of Tfam deficiency occur with age. SIRT1 is an activator of... 19 Jan 2007.
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Reid M. on NEWS: Cold Spring Harbor: A Grab Bag from the Drug Discovery Folks, It's interesting that Scott Small has found that defects in the retromer trafficking complex... 8 Jan 2007.
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Reid M. on NEWS: Beyond γ-Secretase: FAD Mutations Affect Calcium Channel via Lipid Messenger, I have proposed that DFMO, an inhibitor of ornithine decarboxylase, may be a beneficial... 12 Dec 2006.
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Reid M. on NEWS: SfN: The Old and the New—BACE and Cathepsin B Share the β-secretase Stage, Taha and colleagues (1) find that sphingosine kinase-1 is a substrate for cathepsin B. I note... 28 Nov 2006.
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Reid M. on NEWS: Thanks for the Memories—KIBRA Alleles Predict Top Memory Performers, A recent study by Lauriat and colleagues (1) identifies KIBRA, HAX-1 (antiapoptotic... 30 Oct 2006.
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Reid M. on NEWS: Too Little Acetylcholine, Too Much Dopamine Spell Trouble for Neurons, Speaking of α-synuclein, Kim and colleagues (1) report that Dyrk1A, a dual-specificity... 19 Sep 2006.
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Reid M. on NEWS: Madrid: Pooled Antibody Cocktail, New Metal Quencher, IVIg is also used to treat hyper-IgM syndrome. Grewal and colleagues (1) report that protein... 19 Sep 2006.
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Reid M. on NEWS: Aggregation/Disaggregation: Longevity Genes Protect Worms Against Aβ Toxicity, Is there any evidence of pancreatitis prior to the development of AD which may explain the large... 17 Aug 2006.
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Reid M. on NEWS: Madrid: BACE News Roundup, Part 3, It’s of great interest that Guiseppina Tesco and Rudy Tanzi find that caspase-3 degrades GGA3,... 17 Aug 2006.
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Reid M. on NEWS: Crystal Ball for AD? Studies Quantitate Risk Factors, Markers of Progression, Hypertension, obesity, and high cholesterol levels, signs also reported in hypercortisolism, all... 6 Aug 2006.
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Reid M. on PAPER: Salehi A. et al., 2006, The study by Salehi, Delcroix, Mobley, and colleagues reporting that
increased APP expression... 24 Jul 2006.
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Reid M. on NEWS: Linking APP to Apoptosis—p53 Does the Trick, I would also like to propose that another p53 target gene which may be involved in AD is... 23 Jul 2006.
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Reid M. on NEWS: Linking APP to Apoptosis—p53 Does the Trick, It's a very interesting question proposed by Tom Fagan. What is the immediate downstream target... 22 Jun 2006.
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Reid M. on PAPER: Stellwagen D. et al., 2006, David Small (1) reports that amnesia typical of that seen in AD can only be produced when... 31 May 2006.
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1 to 30 of 64 results |
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