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Marchesi V. on NEWS: Combination Drug Trials: Time to Open a New Front in AD?, Questions for thought leaders:
- Why are we putting most of the...
19 Feb 2013.
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Marchesi V. on PAPER: Deane R. et al., 2012, This paper explores the use of two low-molecular-weight compounds that can block the... 11 Apr 2012.
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Marchesi V. on PAPER: Klohs J. et al., 2012, This paper deals with the question of whether small blood vessel damage is a primary factor in... 10 Feb 2012.
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Marchesi V. on PAPER: Sperling RA. et al., 2011, Alzheimer’s dementia is a human problem that is still woefully under-supported and... 13 Dec 2011.
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Marchesi V. on PAPER: Winton MJ. et al., 2011, How can mice with so many genetic defects possibly reflect the pathophysiology of the earliest,... 9 Jun 2011.
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Marchesi V. on NEWS: Committee Shoots Down Florbetapir, Raising Bar for Field at Large, When brain scans to detect protein deposits in the brains of Alzheimer’s patients were first... 26 Jan 2011.
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Marchesi V. on NEWS: What Do Clinicians Say? Peers Welcome Revised Criteria, Few would disagree with the view that knowing the cause of a disease greatly enhances the... 13 Aug 2010.
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Marchesi V. on NEWS: DIAN Dispatch from Hawaii: Glimpse at Data, Push for Trials, One can only applaud the courage and commitment of the investigators involved in this study. It... 23 Jul 2010.
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Marchesi V. on NEWS: Inside Out—Plaques May Have Intracellular Origin, Two things about this study puzzle me. I don’t understand why the uptake of Aβ peptides by... 28 Jan 2010.
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Marchesi V. on LIVE DISCUSSION: Together at Last, Top Five Biomarkers Model Stages of AD, Some thoughts on this interesting proposal:
This article raises important questions... 19 Jan 2010.
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Marchesi V. on NEWS: ADNI: One-year Data Narrow Field of MRI, FDG-PET Approaches, It seems clear that modern scanning methods have essentially replaced the tissue diagnostic... 26 May 2009.
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Marchesi V. on LIVE DISCUSSION: Do Somatic Mutations Generate Toxic Aβ Peptides in Sporadic Alzheimer Disease?, Dr. Nardelli may have heard of the infamous Willie Sutton, a notorious American bank robber.... 11 Feb 2008.
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Marchesi V. on LIVE DISCUSSION: APP Family: Clues to Function in Health and AD
, The function of APP is an important question with many possible answers, since, like so many... 8 Oct 2007.
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Marchesi V. on LIVE DISCUSSION: Presenilin Loss of Function—Plan B for AD?, The Relevance of APP Mutations
Like Rudy Tanzi, I am impressed by the story that... 27 Feb 2007.
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Marchesi V. on PAPER: Ting JT. et al., 2007, This paper confirms recent studies that demonstrate a decrease in AMPA
receptor activity as a... 2 Jan 2007.
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Marchesi V. on NEWS: AMPA Receptors: Going, Going, Gone in Aβ-exposed Synapses, PSD95 Knockouts, This is a landmark paper on how Aβ peptides might induce synaptic depression by reducing the... 19 Dec 2006.
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Marchesi V. on LIVE DISCUSSION: Gain or Loss of Function—Time to Shake up Assumptions on γ-Secretase in Alzheimer Disease?, Peter Davies was too modest to proclaim, as he did in his closing comment, that he would be... 24 May 2006.
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Marchesi V. on NEWS: Aβ Star is Born? Memory Loss in APP Mice Blamed on Oligomer, To their credit, the authors have attempted to look for early changes in the TG 2576 mouse... 27 Mar 2006.
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Marchesi V. on PAPER: Marchesi VT. et al., 2005, Vincent Marchesi: Summary and Impressions
It is a measure of the maturity of the... 23 Nov 2005.
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Marchesi V. on LIVE DISCUSSION: Messing with the Membrane—An Alternative Interpretation of the Amyloid-β Hypothesis, Vincent Marchesi: Summary and Impressions
It is a measure of the maturity of the... 23 Nov 2005.
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Marchesi V. on PAPER: Marchesi VT. et al., 2005, Reply by Vincent Marchesi to comment by Karen Ashe
Based on her recent... 5 Nov 2005.
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Marchesi V. on LIVE DISCUSSION: Messing with the Membrane—An Alternative Interpretation of the Amyloid-β Hypothesis, Reply by Vincent Marchesi to comment by Karen Ashe
Based on her recent... 5 Nov 2005.
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Marchesi V. on PAPER: Marchesi VT. et al., 2005, Dr. Holtzman is correct to point out that my views on the possible fate of cleaved Aβ peptides... 14 Oct 2005.
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Marchesi V. on LIVE DISCUSSION: Messing with the Membrane—An Alternative Interpretation of the Amyloid-β Hypothesis, Dr. Holtzman is correct to point out that my views on the possible fate of cleaved Aβ peptides... 14 Oct 2005.
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Marchesi V. on PAPER: Zurbriggen R. et al., 2005, This paper is an important contribution to the still unsettled issue of immunization as a... 12 Oct 2005.
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Marchesi V. on PAPER: Marchesi VT. et al., 2005, Response by Vincent Marchesi to comments through 28 September 2005
Dr.... 6 Oct 2005.
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Marchesi V. on LIVE DISCUSSION: Messing with the Membrane—An Alternative Interpretation of the Amyloid-β Hypothesis, Response by Vincent Marchesi to comments through 28 September 2005
Dr.... 6 Oct 2005.
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Marchesi V. on NEWS: Nicastrin—A DAPper Role in γ-Secretase, The strength of this paper is the imaginative use of carefully crafted recombinant peptides to... 23 Aug 2005.
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Marchesi V. on NEWS: Amyloid Hypothesis—Closing the Spigot Helps, Temporarily, This paper is one of the most interesting contributions of the year, and may well be one of the... 2 Aug 2005.
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Marchesi V. on PAPER: Janoshazi A. et al., 2006, I can't say that I agree with Paul Coleman's evaluation of this work. The method of analysis is... 31 May 2005.
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1 to 30 of 53 results |
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