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1 to 30 of 51 results |
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Hardy J. on NEWS: Genetics Project Update: Over 1,000 Genomes and Counting, Clearly, the 1000 Genomes Project and related projects are very important for those of us who... 6 Nov 2012.
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Hardy J. on PAPER: Logue MW. et al., 2011, It is very difficult to carry out a genetic analysis of African-Americans for locus discovery... 16 Dec 2011.
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Hardy J. on PAPER: Sperling RA. et al., 2011, Sperling and colleagues cite three possible reasons why amyloid-targeted therapies may not yet... 14 Dec 2011.
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Hardy J. on NEWS: Next-Generation Sequencing: Boldly Going Where No Geneticist..., These papers detailing the pilot part of the 1000 Genomes project really mark an enormous... 5 Nov 2010.
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Hardy J. on PAPER: Sebastiani P. et al., 2010, My view of this study is that it is generally underpowered and that, apart from alleles with... 5 Jul 2010.
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Hardy J. on NEWS: Good Gene, Bad Gene?—New APP Variant May Be Both, The identification of two families with homozygous APP variants ( 17 Mar 2009.
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Hardy J. on NEWS: SORLA Soars—Large Study Links Gene to Late-onset AD, This work is welcome news from an excellent group of investigators. They will surely allow me to... 15 Jan 2007.
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Hardy J. on PAPER: Caffrey TM. et al., 2006, This paper by Caffrey and colleagues suggests that the H1 association between tau and... 8 Dec 2006.
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Hardy J. on NEWS: Highs and Lows: Overactive Synuclein Promoter Linked to Parkinson’s, Tau Loss to Mental Retardation, This work confirms the association between synuclein and Parkinson disease (PD), which has been... 17 Aug 2006.
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Hardy J. on NEWS: Birds of a Feather…Mutations in Tau Gene Neighbor Progranulin Cause FTD, The identification of progranulin mutations by Baker and colleagues is a major advance in our... 17 Jul 2006.
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Hardy J. on NEWS: Charting Genetic Diversity—First Haplotype Map Appears, With the completion of the HapMap and its commercialization by Illumina and Affymetrix, it... 1 Nov 2005.
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Hardy J. on PAPER: Delabar JM. et al., 1987, This paper is wrong, of course. 17 Oct 2005.
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Hardy J. on NEWS: Alzheimer’s Vaccine: In Some Patients, at Least, It Might Just Work, This an extremely interesting preliminary report. The editorial by Winblad and Blum is very... 21 May 2003.
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Hardy J. on PAPER: Abraham R. et al., 2001, Reply to comment by Rudy Tanzi.
Phillipp Kahle's and Bart De Strooper's comments on the... 14 Apr 2003.
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Hardy J. on PAPER: Koide T. et al., 2002, An interesting and provocative paper. If the M232R mutation is pathogenic, then this suggests... 25 Dec 2002.
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Hardy J. on PAPER: Asante EA. et al., 2002, This is a very surprising finding which may suggest that the incidence of BSE-caused CJD is... 4 Dec 2002.
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Hardy J. on PAPER: Parton MJ. et al., 2002, This is a fascinating problem. Why should a mutation on one haplotypic background be recessive,... 27 Nov 2002.
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Hardy J. on PAPER: Liu Y. et al., 2002, A very interesting paper: I caution still, however, that a genetic role for UCH-L1 in... 14 Nov 2002.
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Hardy J. on PAPER: Poorkaj P. et al., 2002, This mutation is particularly intersting in its position... not near the microtubule binding... 14 Nov 2002.
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Hardy J. on PAPER: Eimer S. et al., 2002, So much that has been important for the understanding of APP biology has come from C elegans... 6 Nov 2002.
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Hardy J. on PAPER: Laferla FM. et al., 2002, A great review of an increasingly interesting area 6 Nov 2002.
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Hardy J. on PAPER: Schenk D. et al., 2002, The immunization story has really been a rollercoaster ride of excitement and then despair. ... 9 Oct 2002.
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Hardy J. on PAPER: Lee SF. et al., 2002, This, and the remarkable paper from from Francis and colleagues ( 3 Oct 2002.
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Hardy J. on PAPER: Zubenko GS. et al., 2002, In this paper, the expression "10cM resolution": is misleading because linkage disequilibrium... 9 Jul 2002.
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Hardy J. on PAPER: Heber S. et al., 2000, A heroic and painstaking study… but we still don't really know what APP does. 3 Jul 2002.
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Hardy J. on PAPER: Li YM. et al., 2000, Now proven almost beyond reasonable doubt: presenilin = gamma secretase. The three papers almost... 3 Jul 2002.
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Hardy J. on PAPER: Haugabook SJ. et al., 2001, "An interesting paper which shows yet another way of reducing plaque load... as a result of the... 30 Jun 2002.
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Hardy J. on PAPER: Christie RH. et al., 2001, An amazing technology used to show, once and for all, that plaques are dynamic structures. A... 30 Jun 2002.
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Hardy J. on PAPER: Cai H. et al., 2001, "Excellent paper establishing BACE as b -scretase." 30 Jun 2002.
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 The ALS Forum is a web-based collaborative effort to bring together valuable ALS-related resources for use by researchers worldwide in both academia and industry-based settings.
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Should the FDA be allowed to use data from overseas clinical trials? |
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Absolutely, we are running out of viable subjects in the U.S. |
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9 |
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Yes, so long as the data is reliable |
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31 |
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No, the trials are not as rigorous |
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No, the data should be repeated in the U.S. |
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No, the drug sponsors are just trying to cut corners |
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Responses: 51 |
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