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Cookson M. on PAPER: Chan D. et al., 2011, This paper by Chan et al. develops the previous reports of an effect of LRRK2 on neurite length... 4 Apr 2011.
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Cookson M. on PAPER: Lin CH. et al., 2010, This study by Lin et al. provides an excellent opportunity to reevaluate the proposed role of... 21 Oct 2010.
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Cookson M. on NEWS: Research Brief: A Better Mouse Model of Parkinson Disease?, A progressive, and eventually dramatic, depletion of dopamine-containing neurons that project... 12 Jun 2009.
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Cookson M. on NEWS: Multiple Hits Explain Selective Loss of Dopamine Neurons in PD, One of the difficulties with the longstanding idea that dopamine is a contributor to neuronal... 4 May 2009.
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Cookson M. on NEWS: Parkinson Pathways Branch Out in Flies and Mice, The paper by Whitworth and colleagues adds to the work of Plun-Favreau suggesting that there is... 30 Sep 2008.
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Cookson M. on NEWS: A PD Trifecta: Synuclein Gene Expression, Aging, and Inflammation, I do think this is an interesting study. The possibility that GATA-1 in peripheral tissues, and... 29 Jul 2008.
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Cookson M. on PAPER: Seo H. et al., 2007, The idea that proteasome dysfunction occurs in several neurodegenerative disorders has received... 8 Mar 2007.
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Cookson M. on PAPER: Ekstrand MI. et al., 2007, This paper supports the longstanding hypothesis that mitochondrial derangements are sufficient... 18 Jan 2007.
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Cookson M. on PAPER: MacLeod D. et al., 2006, This paper shows in a striking way that the Lrrk2 gene, which is associated with dominantly... 28 Nov 2006.
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Cookson M. on NEWS: PARK9 Is Unveiled—Mutations Compromise Orphan Lysosomal ATPase, The important question when thinking about the exciting identification of ATP13A2 mutations by... 12 Sep 2006.
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Cookson M, Singleton A. on PAPER: Clark IE. et al., 2006, A central goal for many of us working on the molecular biology of Parkinson disease (PD) has... 12 May 2006.
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Cookson M, Singleton A. on NEWS: More Than a Lark? PD Mutations Increase Kinase Activity, The most important new result, of which there are several, in this well-written paper from the... 4 Nov 2005.
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Cookson M. on PAPER: Seok Ko H. et al., 2005, This paper shows how critical it is to differentiate between observations that are real in the... 1 Sep 2005.
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Cookson M, Miller D. on NEWS: DJ-1 Dances with Daxx to Keep Neurons Spry, The observation that DJ-1 is capable of protecting cells against oxidant-induced cell death has... 29 Jun 2005.
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Cookson M. on PAPER: Masliah E. et al., 2005, It seems increasingly likely that α-synuclein is central to the pathogenesis of Parkinson... 17 Jun 2005.
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Cookson M. on NEWS: Search and Rescue in Parkin Fly Mutants—DA Neurons Are Lost, but Saved by GST, The main novel observation in this very exciting paper from Whitworth and colleagues is that... 2 Jun 2005.
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Cai H, Cookson M. on NEWS: PD Models: Loss of DJ Throws D2 Dopamine Receptor Out of Step, Recessive mutations, like those in DJ-1 that are associated with Parkinsonism, are great... 10 Feb 2005.
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Cookson M. on NEWS: Not Just a Family Affair: Dardarin Mutations Predict Sporadic PD, These papers show that the G2019S mutation in LRRK2/dardarin is the most common single gene... 20 Jan 2005.
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Cookson M. on PAPER: Kalia SK. et al., 2004, The experiments presented by the Lazano group are solid because the authors have been careful to... 20 Dec 2004.
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Cookson M. on PAPER: Lo Bianco C. et al., 2004, This elegant paper extends observations previously made in tissue culture (Petrucelli et al.,... 7 Dec 2004.
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Cookson M. on NEWS: A Step Toward Therapeutic RNA Interference, Many groups have adopted siRNA or shRNA technologies as the method of choice for gene knockdown... 16 Nov 2004.
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Canet-Aviles R, Cookson M. on NEWS: DJ Chaperones α-Synuclein—Offers Cell Model of Parkinson Disease, In this study, Shendelman and coworkers report that DJ-1 inhibits α-synuclein aggregation, and... 8 Oct 2004.
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Cookson M. on NEWS: Lysosomes and Proteasomes Compete for PD Researchers' Attention, Impaired Degradation of Mutant α-Synuclein by Chaperone-Mediated... 9 Sep 2004.
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Cookson M. on NEWS: Parkinson's Omnibus—Vaccination, New Rat Model, and More, What a great group of papers...
From my perspective, the most thrilling paper is the one from... 29 Jun 2004.
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Cookson M. on NEWS: Pink Mutations Link Parkinson’s Disease to Mitochondria, The cloning of the gene for the PARK6 locus by Enza-Maria Valente and her colleagues now gives... 15 Apr 2004.
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Cookson M. on NEWS: What the Fly Forgot—Aβ Expression in Drosophila, The generation and phenotyping of Aβ40- and Aβ42-specific Drosophila transgenic lines... 12 Apr 2004.
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Cookson M. on NEWS: Loss of Parkin in Mammals Takes Steam Out of Mitochondria, This is a great paper. The parkin mice were surprisingly phenotype-free, which seemed a... 14 Mar 2004.
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Cookson M. on NEWS: RNAi Struts Its Stuff in Brain, in Vivo, Tools to selectively knock down specific mRNA species in cells and tissues have developed at a... 8 Dec 2003.
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Cookson M. on NEWS: Spotlight on the DJ: Crystal Structure Solved of Parkinson's Protein, The solution of the crystal structure of DJ-1 is indeed a great step forward, and the... 16 Jun 2003.
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Cookson M. on PAPER: Taylor DM. et al., 2003, Following on from earlier work from the Takahashi lab showing that parkin ubiquitinates pael-r... 8 Apr 2003.
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1 to 30 of 32 results |
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