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Shineman D. on NEWS: Guidelines at Nature Aim to Stem Tide of Irreproducibility, The issue of reproducibility is an important one which also plagues funding organizations that... 14 May 2013.
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Small D. on NEWS: Guidelines at Nature Aim to Stem Tide of Irreproducibility, It is great to see this issue brought out of the closet. It is, of course, a great frustration... 14 May 2013.
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Ning T. on PAPER: de la Torre JC. et al., 2010, Recommendation Only. 14 May 2013.
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Barres B. on PAPER: Benner EJ. et al., 2013, I think this result is quite interesting and important. Reactive astrocytosis is a dramatic... 13 May 2013.
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Heneka M. on PAPER: Zhang G. et al., 2013, Zhang and colleagues conducted experiments to prove a connection among hypothalamic function,... 13 May 2013.
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Duyckaerts C. on NEWS: Endocytosis Pulls α-Secretase From Synapses, I read this paper by Marcello et al. with much interest, and I was impressed both by the number... 13 May 2013.
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Saftig P. on NEWS: Endocytosis Pulls α-Secretase From Synapses, A disintegrin and metalloproteinase 10 (ADAM10) is apparently one of the most critical... 13 May 2013.
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Cirrito J. on NEWS: Endocytosis Pulls α-Secretase From Synapses, Marcello and colleagues demonstrate that synaptic activity regulates the levels of ADAM10 on the... 13 May 2013.
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Piazza F. on PAPER: Piazza F. et al., 2013, Recommendation Only. 10 May 2013.
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Pimplikar S. on NEWS: Gammagard™ Misses Endpoints in Phase 3 Trial, With every AD clinical trial having missed primary endpoints and therefore being deemed as... 10 May 2013.
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Calon F. on NEWS: Gammagard™ Misses Endpoints in Phase 3 Trial, We clearly need to wait until the release of the complete data before drawing conclusions.... 10 May 2013.
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Mairet-Coello G, Polleux F. on PAPER: Mairet-Coello G. et al., 2013, We would like to thank Dr. Sylvain Lesne for his interest in our work and for his comments. We... 10 May 2013.
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Kile S. on NEWS: Gammagard™ Misses Endpoints in Phase 3 Trial, Prior to commenting, I need to disclose that I am the principal investigator of an ongoing IVIG... 8 May 2013.
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Relkin N. on NEWS: Gammagard™ Misses Endpoints in Phase 3 Trial, The topline results were announced today to satisfy SEC requirements and Baxter's obligation to... 8 May 2013.
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Sperling R. on NEWS: Gammagard™ Misses Endpoints in Phase 3 Trial, The IVIG results are very disappointing, as this means we are likely at least two to three years... 8 May 2013.
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Gouras G. on PAPER: Dolev I. et al., 2013, This is a wonderful study by Dolev et al. that underscores why we need more experts in synapse... 8 May 2013.
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Masters C. on NEWS: As DIAN’s Scope Widens, Funding Narrows, Sanjay Pimplikar is a regular commentator on Alzforum. In the current comments, I think the view... 8 May 2013.
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Tariot P. on NEWS: Not Seeing Eye to Eye: Do Lenses Accumulate Aβ?, There appear to be major differences in the quality of the stained images between the two... 8 May 2013.
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Noebels J. on NEWS: Stem Cells Treat Epileptic Symptoms in Mice, Loss of synaptic inhibition is a well-established cause of seizures, and this new study supports... 8 May 2013.
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Goetz J. on PAPER: Karpova A. et al., 2013, Recommendation Only. 8 May 2013.
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Gross M. on PAPER: Horváth S. et al., 2001, Recommendation Only. 8 May 2013.
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Choi M. on PAPER: Gavrilova SI. et al., 2011, Recommendation Only. 8 May 2013.
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Goetz J. on PAPER: Lu J. et al., 2013, Interesting finding. 8 May 2013.
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Mattson M. on NEWS: Do Microglia in the Hypothalamus Drive Aging?, A Hypothalamus-Centric Inflammation-Mediated View of Aging. What About Energy... 3 May 2013.
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Calon F. on NEWS: Can Transferrin Antibodies Safely Open the Blood-Brain Barrier?, The search for brain drug delivery vectors has not yielded much success. Therefore, the... 3 May 2013.
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Pimplikar S. on NEWS: As DIAN’s Scope Widens, Funding Narrows, Some of the events highlighted in Alzforum over the last two weeks underscore the challenge... 2 May 2013.
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Figueiredo-Pereira M. on PAPER: Orre M. et al., 2013, This very interesting paper uses state-of-the-art techniques to assess properties of unique... 1 May 2013.
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Musiek E. on NEWS: ApoE Does Not Bind Aβ, Competes for Clearance, Recommendation Only. 1 May 2013.
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Kamal M. on PAPER: Grimbergen YA. et al., 2009, Good paper. 1 May 2013.
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Nielsen H. on PAPER: Verghese PB. et al., 2013, In this paper, Verghese et al. provide important data confirming earlier studies showing reduced... 1 May 2013.
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