The intracellular domain of the beta-amyloid precursor protein is stabilized by Fe65 and translocates to the nucleus in a notch-like manner. - AlzForum Alzheimer Research Paper of the Week


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Home: Papers of the Week

Annotation

	Kimberly WT, Zheng JB, Guénette SY, Selkoe DJ. The intracellular domain of the beta-amyloid precursor protein is stabilized by Fe65 and translocates to the nucleus in a notch-like manner. J Biol Chem. 2001 Oct 26;276(43):40288-92. PubMed Abstract

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	Comment by: Benjamin Wolozin, ARF Advisor (Disclosure)
	Permalink
	Recent findings suggest that APP stimulates gene transcription. This study provides important confirmation for that observation. View all comments by Benjamin Wolozin

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