Jimenez S, Baglietto-Vargas D, Caballero C, Moreno-Gonzalez I, Torres M, Sanchez-Varo R, Ruano D, Vizuete M, Gutierrez A, Vitorica J.
Inflammatory response in the hippocampus of PS1M146L/APP751SL mouse model of Alzheimer's disease: age-dependent switch in the microglial phenotype from alternative to classic.J Neurosci.
2008 Nov 5;28(45):11650-61.
Submit a Comment on this Paper
REAGENTS/MATERIAL: Primary antibodies used in this study included: Western blot and dot blot:
monoclonal mouse anti-Aβ1-16 (6E10) (Sigma-Aldrich);
monoclonal mouse anti-Aβ oligomers (Nu-1) (courtesy of Drs. W. Klein and M. Lambert, Northwestern University, Evanston, IL) and
monoclonal mouse anti-Aβ oligomers (A11) (Biosource Invitrogen). Immunohistochemistry:
monoclonal mouse anti-Aβ (6E10) (Sigma Aldrich);
monoclonal rat anti-CD11b (Serotec);
chicken anti-GFAP (Dako);
monoclonal Hamster anti-CD3 (BD PharMingen);
monoclonal rat anti-TNFα (MP6-XT22) (Abcam);
rabbit anti-iNOS (Transduction Laboratories);
goat anti-IL4 (SantaCruz)
and goat anti-AMCase (YM-1) (SantaCruz)