Non-cell-autonomous effects of presenilin 1 variants on enrichment-mediated hippocampal progenitor cell proliferation and differentiation. - AlzForum Alzheimer Research Paper of the Week


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Home: Papers of the Week

Annotation

	Choi SH, Veeraraghavalu K, Lazarov O, Marler S, Ransohoff RM, Ramirez JM, Sisodia SS. Non-cell-autonomous effects of presenilin 1 variants on enrichment-mediated hippocampal progenitor cell proliferation and differentiation. Neuron. 2008 Aug 28;59(4):568-80. PubMed Abstract

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REAGENTS/MATERIAL:
The antibodies we used were:
rat monoclonal anti-BrdU (BU1/75 ICR1) (Accurate Chemical & Scientific, Westbury, NY); mouse monoclonal anti-BrdU (85-2C8) (Novocastra, Newcastle, United Kingdom); goat polyclonal anti-doublecortin (Dr. Gerd Kempermann, Charité University, Berlin, Germany); mouse monoclonal anti-NeuN (A60) (Chemicon, Temecula, CA); mouse monoclonal anti-βIII-tubulin (TUJ1) (Covance Research Products, Denver, PA); mouse monoclonal anti-oligodendrocyte marker O4 (81) (Stem Cell Technologies, Toronto, Canada); rabbit polyclonal anti-GFAP (Dako, Fort Collins, CO); rabbit polyclonal anti-s100β (Swant, Bellinzona, Switzerland); rabbit polyclonal anti-Iba1 (Wako, Osaka, Japan), with a FITCconjugated Bandeiraea simplicifolia Isolectin B4 (IB-4), (Sigma, St. Louis, MO); mouse monoclonal anti-Nestin (R-401) (Dr. Daniel H. Geschwind, UCLA, California, US) and polyclonal antibodies that detect epitopes in the PS1-NTF or PS1-CTF (Kim and Sisodia, 2005)