Alpha7 nicotinic acetylcholine receptor expression by vascular smooth muscle cells facilitates the deposition of Abeta peptides and promotes cerebrovascular amyloid angiopathy. - AlzForum Alzheimer Research Paper of the Week


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Home: Papers of the Week

Annotation

	Clifford PM, Siu G, Kosciuk M, Levin EC, Venkataraman V, D'Andrea MR, Nagele RG. Alpha7 nicotinic acetylcholine receptor expression by vascular smooth muscle cells facilitates the deposition of Abeta peptides and promotes cerebrovascular amyloid angiopathy. Brain Res. 2008 Oct 9;1234:158-71. PubMed Abstract

	Comments on Paper and Primary News

	Comment by: George Perry (Disclosure)
	Submitted 3 September 2008 \| Permalink	Posted 5 September 2008
	I recommend this paper

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REAGENTS/MATERIAL:
Immunohistochemical analyses were performed using the following antibodies:
rabbit anti-Aβ42 (Chemicon International, Temecula, CA; rabbit anti-Aβ42 (BD Pharmingen, San Diego, CA); rabbit anti-Aβ40 (Chemicon International, Temecula, CA); mouse monoclonal anti-α7 nicotinic acetylcholine receptor (mAb 306) (Sigma Aldrich, St. Louis, MO) and mouse monoclonal anti-smooth muscle actin (1A4) (Sigma Aldrich, St. Louis, MO)




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