McLean CA, Cherny RA, Fraser FW, Fuller SJ, Smith MJ, Beyreuther K, Bush AI, Masters CL.
Soluble pool of Abeta amyloid as a determinant of severity of neurodegeneration in Alzheimer's disease.Ann Neurol.
PubMed Abstract, View on AlzSWAN
This report shifts the importance of Abeta in AD from the amyloid depositions to a soluble Abeta peptide. This shift is nessasary as there is good evidence that amyloid plaques may not be responsible for AD.