Overexpression of ABCA1 reduces amyloid deposition in the PDAPP mouse model of Alzheimer disease. - AlzForum Alzheimer Research Paper of the Week


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Home: Papers of the Week

Annotation

	Wahrle SE, Jiang H, Parsadanian M, Kim J, Li A, Knoten A, Jain S, Hirsch-Reinshagen V, Wellington CL, Bales KR, Paul SM, Holtzman DM. Overexpression of ABCA1 reduces amyloid deposition in the PDAPP mouse model of Alzheimer disease. J Clin Invest. 2008 Feb;118(2):671-82. PubMed Abstract, View on AlzSWAN

	Comments on Paper and Primary News

	Comment by: George Perry (Disclosure)
	Submitted 8 February 2008 \| Permalink	Posted 9 February 2008
	I recommend this paper

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REAGENTS/MATERIAL:
Antibodies used in this study are:
rat anti-GCNA1 (George Enders, University of Kansas Medical Center); goat anti-GATA4 (Santa Cruz); mouse monoclonal anti-ABCA1 (HJ1) (David Holtzman); rabbit anti-apoA-I (Biodesign); goat anti-apoE (Calbiochem); rabbit anti-apoJ (Signet Covance); rabbit anti-apoAPP (Zymed); rabbit monoclonal anti-LDLR (EP1553Y) (Novus); rabbit anti-LRP (Guojun Bu, Washington University); rabbit anti-ABCG1 (Novus); and mouse monoclonal anti-tubulin (B-5-1-2) (Sigma-Aldrich)