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Home: Papers of the Week
Annotation


Ancolio K, Dumanchin C, Barelli H, Warter JM, Brice A, Campion D, Frébourg T, Checler F. Unusual phenotypic alteration of beta amyloid precursor protein (betaAPP) maturation by a new Val-715 --> Met betaAPP-770 mutation responsible for probable early-onset Alzheimer's disease. Proc Natl Acad Sci U S A. 1999 Mar 30;96(7):4119-24. PubMed Abstract

Comments on Paper and Primary News
  Comment by:  Hiroshi Mori, ARF Advisor
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This contains an important mutation which may provide a new insight for amyloidogenesis and two amyloid species.

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