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Home: Papers of the Week
Annotation


Siman R, Reaume AG, Savage MJ, Trusko S, Lin YG, Scott RW, Flood DG. Presenilin-1 P264L knock-in mutation: differential effects on abeta production, amyloid deposition, and neuronal vulnerability. J Neurosci. 2000 Dec 1;20(23):8717-26. PubMed Abstract, View on AlzSWAN

Comments on Paper and Primary News
  Comment by:  Eddie Koo, ARF Advisor
Permalink

Very interesting knock-in transgenic mice models where neither APP nor PS were overexpressed.

View all comments by Eddie Koo
  Comment by:  Benjamin Wolozin, ARF Advisor (Disclosure)
Permalink

Important clarification in an ongoing debate.

View all comments by Benjamin Wolozin
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