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Home: Papers of the Week
Annotation


Hamanaka H, Katoh-Fukui Y, Suzuki K, Kobayashi M, Suzuki R, Motegi Y, Nakahara Y, Takeshita A, Kawai M, Ishiguro K, Yokoyama M, Fujita SC. Altered cholesterol metabolism in human apolipoprotein E4 knock-in mice. Hum Mol Genet. 2000 Feb 12;9(3):353-61. PubMed Abstract

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  Comment by:  Hiroshi Mori, ARF Advisor
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The present mice could be very useful and important for analyzing lipid turnover and amyloid deposition because their apoE is in situ regulated in a physiological fashion.

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