Unraveling in vivo functions of amyloid precursor protein: insights from knockout and knockdown studies. - AlzForum Alzheimer Research Paper of the Week


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Home: Papers of the Week

Annotation

	Senechal Y, Larmet Y, Dev KK. Unraveling in vivo functions of amyloid precursor protein: insights from knockout and knockdown studies. Neurodegener Dis. 2006;3(3):134-47. PubMed Abstract

	Comments on Paper and Primary News

	Comment by: Andre Delacourte
	Submitted 13 September 2006 \| Permalink	Posted 18 September 2006
	I recommend this paper

	Comment by: Takaomi Saido, ARF Advisor
	Submitted 14 September 2006 \| Permalink	Posted 19 September 2006
	I recommend this paper Biological functions of APP may be secondary as compared to pathogenic effects of Aβ in the study of Alzheimer disease. It is, however, still important to understand the role and regulation of APP because APP expression seems to be upregulated after Aβ accumulates in the brain to some extent. View all comments by Takaomi Saido

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