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Home: Papers of the Week
Annotation


Li Y, Grupe A, Rowland C, Nowotny P, Kauwe JS, Smemo S, Hinrichs A, Tacey K, Toombs TA, Kwok S, Catanese J, White TJ, Maxwell TJ, Hollingworth P, Abraham R, Rubinsztein DC, Brayne C, Wavrant-De Vrièze F, Hardy J, O'Donovan M, Lovestone S, Morris JC, Thal LJ, Owen M, Williams J, Goate A. DAPK1 variants are associated with Alzheimer's disease and allele-specific expression. Hum Mol Genet. 2006 Sep 1;15(17):2560-8. PubMed Abstract, View on AlzGene

Comments on Paper and Primary News
  Comment by:  Lars Bertram
Submitted 14 June 2007  |  Permalink Posted 16 June 2007

From the AlzGene team:
Note that only approximately 25-30 percent of the markers that were tested in the chromosome-wide association (CWA) analyses (Grupe et al., 2006 and Li et al., 2006) were also tested in the genome-wide association (GWA) study (Grupe et al., 2007). In particular, markers from the two "featured genes" identified in the CWA (in DAPK and LOC439999) were not included in the GWA. We thank Dr. Grupe for supplying this additional information.

View all comments by Lars Bertram
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