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Home: Papers of the Week
Annotation


Peskind ER, Li G, Shofer J, Quinn JF, Kaye JA, Clark CM, Farlow MR, Decarli C, Raskind MA, Schellenberg GD, Lee VM, Galasko DR. Age and apolipoprotein E*4 allele effects on cerebrospinal fluid beta-amyloid 42 in adults with normal cognition. Arch Neurol. 2006 Jul;63(7):936-9. PubMed Abstract, View on AlzSWAN

Comments on Related Papers
  Related Paper: CSF tau/Abeta42 ratio for increased risk of mild cognitive impairment: a follow-up study.

Comment by:  John Trojanowski, ARF Advisor
Submitted 24 August 2007  |  Permalink Posted 27 August 2007
  I recommend this paper

This study is important for providing data and insight on strategies for attempting to detect latent or prodromal AD at the pre-MCI stage. This approach could be incorporated into early detection methods that will be increasingly relevant once effective preventive interventions are available.

View all comments by John Trojanowski
  Related Paper: The effects of normal aging and ApoE genotype on the levels of CSF biomarkers for Alzheimer's disease.

Comment by:  John Trojanowski, ARF Advisor
Submitted 13 October 2007  |  Permalink Posted 14 October 2007
  I recommend this paper
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CSF tau/Abeta42 ratio for increased risk of mild cognitive impairment: a follow-up study.

The effects of normal aging and ApoE genotype on the levels of CSF biomarkers for Alzheimer's disease.
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