Pal A, Severin F, Lommer B, Shevchenko A, Zerial M. Huntingtin-HAP40 complex is a novel Rab5 effector that regulates early endosome motility and is up-regulated in Huntington's disease. J Cell Biol. 2006 Feb 13;172(4):605-18. PubMed Abstract
RELATED PAPERSRab5-stimulated up-regulation of the endocytic pathway increases intracellular levels of betaCTFs and Abeta production.