It would certainly make sense if the medial temporal lobe is affected early and perhaps most agressively by AD, as the early clinical symptoms seems to suggest. Molecular studies also indicate that enzymatic activity is changed profoundly initially in both the temporal lobe and the hippocampus buried deep inside it.

References:
Cecil textbook of medicine... Encyclopedia of Alzheimers.

View all comments by Jacob Mack

This is fascinating information. I believe we are just beginning to see the potential of fMRI in the field of neuroscience. Much of my current research involves fMRI in the study of mirror neurons, and I encourage new scientists to consider further exploration of fMRI in AD research applications.

View all comments by J. Lucy Boyd