Proteomic and functional analyses reveal a mitochondrial dysfunction in P301L tau transgenic mice. - AlzForum Alzheimer Research Paper of the Week


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Home: Papers of the Week

Annotation

	David DC, Hauptmann S, Scherping I, Schuessel K, Keil U, Rizzu P, Ravid R, Dröse S, Brandt U, Müller WE, Eckert A, Götz J. Proteomic and functional analyses reveal a mitochondrial dysfunction in P301L tau transgenic mice. J Biol Chem. 2005 Jun 24;280(25):23802-14. PubMed Abstract, View on AlzSWAN

	Comments on Paper and Primary News

	Comment by: Andre Delacourte
	Submitted 22 April 2005 \| Permalink	Posted 24 April 2005
	I recommend this paper

	Comment by: Li-Huei Tsai
	Submitted 24 April 2005 \| Permalink	Posted 24 April 2005
	I recommend this paper

	Comment by: John Trojanowski, ARF Advisor
	Submitted 24 April 2005 \| Permalink	Posted 27 April 2005
	I recommend this paper The study extends insights into the consequences of tau pathology that involve a mitochondrial and oxidative stress. View all comments by John Trojanowski

	Comment by: Nikolaos K. Robakis
	Submitted 24 April 2005 \| Permalink	Posted 27 April 2005
	I recommend this paper An interesting paper, suggesting involvement of mitochondria in fronto-temporal dementia. View all comments by Nikolaos K. Robakis

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REAGENTS/MATERIAL:

TauP301L mice at various ages were used in this study.




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