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Home: Papers of the Week
Annotation


Schwab C, Hosokawa M, McGeer PL. Transgenic mice overexpressing amyloid beta protein are an incomplete model of Alzheimer disease. Exp Neurol. 2004 Jul;188(1):52-64. PubMed Abstract

Comments on Paper and Primary News
  Comment by:  Takaomi Saido, ARF Advisor
Submitted 16 June 2004  |  Permalink Posted 17 June 2004
  I recommend this paper
  Comment by:  Paul Coleman, ARF Advisor
Submitted 16 June 2004  |  Permalink Posted 17 June 2004

The title of this paper should, apparently really be "Transgenic mice overexpressing amyloid beta protein ALONE are an incomplete ----". When expression of mutated APP is combined with expression of other mutated proteins important in AD pathology these t.g. mice exhibit a rich array of AD characteristics (e.g. LaFerla, 2003).

View all comments by Paul Coleman
  Comment by:  Andre Delacourte, ARF Advisor
Submitted 18 June 2004  |  Permalink Posted 19 June 2004
  I recommend this paper
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