The Parkinson's disease protein DJ-1 is neuroprotective due to cysteine-sulfinic acid-driven mitochondrial localization. - AlzForum Alzheimer Research Paper of the Week


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Annotation

	Canet-Avilés RM, Wilson MA, Miller DW, Ahmad R, McLendon C, Bandyopadhyay S, Baptista MJ, Ringe D, Petsko GA, Cookson MR. The Parkinson's disease protein DJ-1 is neuroprotective due to cysteine-sulfinic acid-driven mitochondrial localization. Proc Natl Acad Sci U S A. 2004 Jun 15;101(24):9103-8. PubMed Abstract

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REAGENTS/MATERIAL:

Antibodies used for Western blotting and/or immunoprecipiations were monoclonal anti-DJ1 (clone 3E8; 1:2,000; Stressgen Biotechnologies), monoclonal anti-V5 (1:5,000, Invitrogen), monoclonal anti-Tim23 (clone 32; 1:2,500; BD Biosciences), monoclonal anti--actin (clone AC-15; 1:5,000; Sigma), and polyclonal anti-VDAC (1:2,500; Abcam).