Chung KK, Thomas B, Li X, Pletnikova O, Troncoso JC, Marsh L, Dawson VL, Dawson TM. S-nitrosylation of parkin regulates ubiquitination and compromises parkin's protective function. Science. 2004 May 28;304(5675):1328-31. PubMed Abstract
REAGENTS/MATERIAL: iNOS deficient and nNOS deficient mice (The Jackson Lab)and wt controls were used in this study. Western blots were probed with anti-ubiquitin (DAKO) or anti-myc or anti-HA antibodies (Roche).
iNOS deficient and nNOS deficient mice (The Jackson Lab)and wt controls were used in this study.
Western blots were probed with anti-ubiquitin (DAKO) or anti-myc or anti-HA antibodies (Roche).
PRIMARY NEWSNO Parkin—A Simple Modification Arrests Ligase