SUMO modification of Huntingtin and Huntington's disease pathology. - AlzForum Alzheimer Research Paper of the Week


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Annotation

	Steffan JS, Agrawal N, Pallos J, Rockabrand E, Trotman LC, Slepko N, Illes K, Lukacsovich T, Zhu YZ, Cattaneo E, Pandolfi PP, Thompson LM, Marsh JL. SUMO modification of Huntingtin and Huntington's disease pathology. Science. 2004 Apr 2;304(5667):100-4. PubMed Abstract

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REAGENTS/MATERIAL:

Primary antibodies were: polyclonal sheep anti-huntingtin S830 (1:500, gift of Dr. G. Bates); rabbit polyclonal anti-Htt CAG53b (1:5000, gift of Erich Wanker); monoclonal anti-Htt mEM48 (1:200, Chemicon MAB5374); rabbit polyclonal anti-SUMO-1 (1:500, Santa Cruz FL101), and mouse monoclonal anti-human SUMO-1 (aa 1-101, Santa Cruz).