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Home: Papers of the Week
Annotation


Andorfer C, Kress Y, Espinoza M, de Silva R, Tucker KL, Barde YA, Duff K, Davies P. Hyperphosphorylation and aggregation of tau in mice expressing normal human tau isoforms. J Neurochem. 2003 Aug;86(3):582-90. PubMed Abstract

Comments on Paper and Primary News
  Comment by:  Todd E. Golde
Submitted 30 July 2003  |  Permalink Posted 3 August 2003
  I recommend this paper

This could be the best model for studying AD like tauopathies, as these mice develop tangles without mutations. The finding that this only occurs when mouse tau is KO'ed is very interesting....

View all comments by Todd E. Golde
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