Sensitive detection of pathological prion protein by cyclic amplification of protein misfolding. - AlzForum Alzheimer Research Paper of the Week


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Annotation

	Saborio GP, Permanne B, Soto C. Sensitive detection of pathological prion protein by cyclic amplification of protein misfolding. Nature. 2001 Jun 14;411(6839):810-3. PubMed Abstract

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REAGENTS/MATERIAL:

Scrapie hamster brain homogenates were immunoblotted with 3F4 anti-PrP antibody, 1:50,000, and a secondary antibody conjugated to HRP then developed with ECL (Amersham).

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