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Home: Papers of the Week
Annotation


Ohkubo N, Lee YD, Morishima A, Terashima T, Kikkawa S, Tohyama M, Sakanaka M, Tanaka J, Maeda N, Vitek MP, Mitsuda N. Apolipoprotein E and Reelin ligands modulate tau phosphorylation through an apolipoprotein E receptor/disabled-1/glycogen synthase kinase-3beta cascade. FASEB J. 2003 Feb;17(2):295-7. PubMed Abstract, View on AlzSWAN

Comments on Paper and Primary News
  Comment by:  Inez Vincent, ARF Advisor
Submitted 17 January 2003  |  Permalink Posted 17 January 2003
  I recommend this paper

This is a beautiful study aimed at unraveling the connection between ApoE, a prominent risk factor for AD, and intracellular signaling and tau phosphorylation. Immunohistochemistry would have been very useful in the interpretation. Perhaps the authors are working on this?

View all comments by Inez Vincent
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