Modulation of beta-amyloid precursor protein processing by the low density lipoprotein receptor-related protein (LRP). Evidence that LRP contributes to the pathogenesis of Alzheimer's disease. - AlzForum Alzheimer Research Paper of the Week


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Home: Papers of the Week

Annotation

	Ulery PG, Beers J, Mikhailenko I, Tanzi RE, Rebeck GW, Hyman BT, Strickland DK. Modulation of beta-amyloid precursor protein processing by the low density lipoprotein receptor-related protein (LRP). Evidence that LRP contributes to the pathogenesis of Alzheimer's disease. J Biol Chem. 2000 Mar 10;275(10):7410-5. PubMed Abstract

	Comments on Paper and Primary News

	Comment by: Hiroshi Mori, ARF Advisor
	Permalink
	It is very interesting and desiralbe to enhance the present study because cerebral LRP blockade may be a new anti-AD therapy. View all comments by Hiroshi Mori

	Comment by: Nikolaos K. Robakis
	Permalink
	This is a very interesting report. As suggested by the authors, it could lead to the discovery of pharmacological agents that decrease amyloid production by acting on LRP. View all comments by Nikolaos K. Robakis

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