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Home: Papers of the Week
Annotation


Calhoun ME, Burgermeister P, Phinney AL, Stalder M, Tolnay M, Wiederhold KH, Abramowski D, Sturchler-Pierrat C, Sommer B, Staufenbiel M, Jucker M. Neuronal overexpression of mutant amyloid precursor protein results in prominent deposition of cerebrovascular amyloid. Proc Natl Acad Sci U S A. 1999 Nov 23;96(24):14088-93. PubMed Abstract

Comments on Paper and Primary News
  Comment by:  Nikolaos K. Robakis
Permalink

An interesting paper because it sheds light on the mechanism of cerebrovascular amyloidosis

View all comments by Nikolaos K. Robakis
Comments on Related Papers
  Related Paper: Spontaneous hemorrhagic stroke in a mouse model of cerebral amyloid angiopathy.

Comment by:  Benjamin Wolozin, ARF Advisor (Disclosure)
Permalink

This is an important article because it validates the relationship between CAA and hemorrhage, which was one of the earliest APP related mutations associated with dementia.

View all comments by Benjamin Wolozin
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