Axonal transport of amyloid precursor protein is mediated by direct binding to the kinesin light chain subunit of kinesin-I. - AlzForum Alzheimer Research Paper of the Week


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Home: Papers of the Week

Annotation

	Kamal A, Stokin GB, Yang Z, Xia CH, Goldstein LS. Axonal transport of amyloid precursor protein is mediated by direct binding to the kinesin light chain subunit of kinesin-I. Neuron. 2000 Nov;28(2):449-59. PubMed Abstract

	Comments on Related Papers

	Related Paper: Kinesin-mediated axonal transport of a membrane compartment containing beta-secretase and presenilin-1 requires APP. Comment by: Benjamin Wolozin, ARF Advisor (Disclosure)
	Permalink
	I recommend this paper Despite intensive study the functions of APP are unknown, however an increasing number of experiments are identifying functions of APP. This paper is interesting because it identifies a function that appears to be dependent on APP which, if true, would be a major function of APP and further the understanding of its basic biology." - Benjamin Wolozin. View all comments by Benjamin Wolozin

	Related Paper: Kinesin-mediated axonal transport of a membrane compartment containing beta-secretase and presenilin-1 requires APP. Comment by: shen chengyong
	Submitted 31 August 2004 \| Permalink	Posted 1 September 2004
	I recommend this paper This paper provided us with a new function mechanism of APP, which may give us some clues as to how to decrease amyloid peptide while not disturbing the normal function of. View all comments by shen chengyong

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