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 I recommend this paper
"It is highly likely that neprilysin is a key molecule to down-regulate of amyloid burden. It is undoubtedly worth to look for a potent in vivo and synthetic activator of neprilysin."  View all comments by Hiroshi Mori |
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I recommend this paper
"The important aspect of the recent work is that chronically diminished enzyme activity (as opposed to acute inhibition) had an effect on Abeta levels. The interesting issue still remaining is whether or not genetic or pharmacologic manipulations will alter amyloid deposition in the mice, and whether there are ways to enhance Abeta degradation." View all comments by Bradley Hyman |
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I recommend this paper
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