The capillary dysfunction hypothesis of Alzheimer's disease. - AlzForum Alzheimer Research Paper of the Week


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Home: Papers of the Week

Annotation

	Ostergaard L, Aamand R, Gutiérrez-Jiménez E, Ho YC, Blicher JU, Madsen SM, Nagenthiraja K, Dalby RB, Drasbek KR, Møller A, Braendgaard H, Mouridsen K, Jespersen SN, Jensen MS, West MJ. The capillary dysfunction hypothesis of Alzheimer's disease. Neurobiol Aging. 2013 Apr;34(4):1018-31. PubMed Abstract

	Comments on Paper and Primary News

	Comment by: Michael Lardelli
	Submitted 14 January 2013 \| Permalink	Posted 16 January 2013
	I recommend this paper A fascinating paper describing how capillary dysfunction would be expected to initially lead to increased cerebral blood flow, followed by a transition to decreased blood flow as Alzheimer's disease progresses. The paper includes extensive and fascinating discussion of how many diverse observations fit into the authors' model. View all comments by Michael Lardelli

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