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Home: Papers of the Week
Annotation


Hong M, Zhukareva V, Vogelsberg-Ragaglia V, Wszolek Z, Reed L, Miller BI, Geschwind DH, Bird TD, McKeel D, Goate A, Morris JC, Wilhelmsen KC, Schellenberg GD, Trojanowski JQ, Lee VM. Mutation-specific functional impairments in distinct tau isoforms of hereditary FTDP-17. Science. 1998 Dec 4;282(5395):1914-7. PubMed Abstract, View on AlzSWAN

  
Comments on Paper and Primary News
  Comment by:  Nikolaos K. Robakis
Permalink

This is an interesting paper as it offers a mechanism by which tau mutations may cause neuronal dysfunction in FTDP-1.

View all comments by Nikolaos K. Robakis
Comments on Related Papers
  Related Paper: Distinct FTDP-17 missense mutations in tau produce tau aggregates and other pathological phenotypes in transfected CHO cells.

Comment by:  Benjamin Wolozin, ARF Advisor (Disclosure)
Permalink
  I recommend this paper

"Important model of aggregation."

View all comments by Benjamin Wolozin
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PRIMARY NEWS
What FTDP-17 Mutations Do

RELATED PAPERS
Distinct FTDP-17 missense mutations in tau produce tau aggregates and other pathological phenotypes in transfected CHO cells.
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