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Home: Papers of the Week
Annotation


Soto C, Sigurdsson EM, Morelli L, Kumar RA, Castaño EM, Frangione B. Beta-sheet breaker peptides inhibit fibrillogenesis in a rat brain model of amyloidosis: implications for Alzheimer's therapy. Nat Med. 1998 Jul;4(7):822-6. PubMed Abstract

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  Related Paper: Immunization with a nontoxic/nonfibrillar amyloid-beta homologous peptide reduces Alzheimer's disease-associated pathology in transgenic mice.

Comment by:  Benjamin Wolozin, ARF Advisor (Disclosure)
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  I recommend this paper

This provides further confirmation of the value of immunization in reducing amyloid burden.

View all comments by Benjamin Wolozin
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Immunization with a nontoxic/nonfibrillar amyloid-beta homologous peptide reduces Alzheimer's disease-associated pathology in transgenic mice.
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