Smith MA, Wehr K, Harris PL, Siedlak SL, Connor JR, Perry G.
Abnormal localization of iron regulatory protein in Alzheimer's disease.Brain Res.
1998 Mar 30;788(1-2):232-6.
PubMed Abstract
IRP-2 but not IRP-1 might be directly linked to impaired iron homeostasis in Alzheimer's disease. Such a specific role may suggest a causal relationship between iron disturbance and AD pathology.