THE HBO ALZHEIMER’S PROJECT

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We are pleased to present exclusive short films from “The Alzheimer’s Project,” sponsored by HBO Documentary Films and the National Institute on Aging of the National Institutes of Health, with support from the Alzheimer’s Association, the Fidelity Charitable Gift Fund, and the Geoffrey Beene Gives Back Alzheimer’s Initiative. This collection of 18 short films brings you additional perspectives, and in-depth scientific discussion, of a broad range of topics in Alzheimer disease research beyond the material broadcast by the main Alzheimer’s Project. In the HBO Alzforum films below, some of the leading scientists in academia and drug development whose work you have come to know over the years speak directly to key issues in AD research today. (To view the project’s four feature films and 15 lay-language supplemental films, go to HBO’s Alzheimer’s Project website; to get up to speed on the overall project, view a brief ARF related news story.) We welcome your comments.

The films are:

1. Searching for Biomarkers: Discussion with the Antecedent Biomarkers Group at Washington University, St. Louis, Missouri. Led by David Holtzman
2. The Default Network Hypothesis: Randy Buckner, Harvard University/Massachusetts General Hospital, Boston
3. The Progress of Drug Development. A group discussion at the 2008 ICAD conference in Chicago, moderated by Maria Carillo of the Alzheimer's Association. Features Paul Aisen, UCSC/ADCS; Richard Frank, GE Healthcare, Russell Katz, FDA; Marcelle Morrison-Bogorad, NIA; Lennart Mucke, UCSF/Gladstone Institute, Dale Schenk, Elan Pharmaceuticals; Eric Siemers, Eli Lilly and Company
4. Approving Drugs for Alzheimer's. A conversation with Russell Katz, FDA
5. Beta-amyloid and Its Different Forms. A Conversation with Eddie Koo, UCSD
6. Advancements in Immunotherapy. A Conversation with Dale Schenk, Elan Pharmaceuticals
7. The Biological Progression of Alzheimer's. A Presentation by Steven DeKosky, University of Virginia School of Medicine
8. Changing the Paradigm: Imaging Amyloid in a Living Human. A Conversation with William Klunk and Chester Mathis, University of Pittsburgh Medical School
9. Rapid Autopsy: Banner Sun Health Research Institute, Sun City, Arizona
10. Understanding Genetics in Alzheimer's Disease. John Hardy, University College, London, Alison Goate, WashU
11. Beta-Amyloid Oligomers: Investigating the Culprits. Dennis Selkoe, Harvard Medical School/Brigham and Women's Hospital, Boston
12. Looking for the Needle in the Electroencephalographic Haystack. A conversation with Lennart Mucke, UCSF/Gladstone Institute
13. Searching for the Cause of Late-Onset Alzheimer's: Retromer Proteins. A presentation by Scott Small, Columbia University Medical Center, New York City
14. Beta-amyloid: Multiple Avenues of Study. A conversation with David Holtzman, Washington University School of Medicine, St. Louis
15. Beyond Amyloid and Tau in Alzheimer's Disease. A conversation with David Bennett, Rush University Medical Center
16. Diagnosing Alzheimer's Disease. A conversation with John Morris, Washington University School of Medicine, St. Louis
17. Distinguishing Between the Mind and the Brain
18. New Perspectives on ApoE and Alzheimer's. Lennart Mucke, UCSF/Gladstone