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1 to 25 of 780 results
Could Longevity Factor, Epilepsy Med, Treat AD One Day?
14  May 2013. At a San Francisco conference addressing Alzheimer’s and related disorders, the agenda featured a diverse mix of topics—occasionally even from the same lab...

  
Paracrine Signal From BACE1-Clipped Neuregulin Rescues Myelin
13  May 2013. As β-secretase inhibitors head into Alzheimer’s disease trials, researchers are paying close attention to what else BACE1 does besides snip amyloid-β from APP...

  
Therapeutic Approaches Target Deubiquitinase, Protein Turnover
10  May 2013. This scientific meeting that drew some 150 researchers to San Francisco 15-17 April 2013 featured an unusually broad array of topics...

  
As DIAN’s Scope Widens, Funding Narrows
25  April 2013. Public funding is becoming so scarce that the DIAN researchers are increasingly asking industry to help...

  
Safe at 4 Grams? No ARIA at High Dose of Human Aβ Antibody
18  April 2013. Researchers showed new data on how a therapeutic Aβ antibody their company had licensed from the Swiss biotech Neurimmune was measuring up...

  
Human-Derived SOD1 Antibodies Show Promise in ALS Mice
17  April 2013. You could say the concept that endogenous proteins in the body can misfold, aggregate, and spread disease from cell to cell has created infectious enthusiasm for drug development...

  
First Stab at Combination Therapy Yields Additive Effect
8  April 2013. The last day of the meeting unfolded as is often the case at long conferences: Some of the most anticipated talks spilled their new data before sparse audiences...

  
Brain Imaging in Trials—How to Make It Work?
5  April 2013. Researchers debated how to put insights from longitudinal biomarker studies to use in the next wave of therapeutic trials, which increasingly include costly PET and MR scans...

  
Longitudinal Data Stand Out at AD/PD Imaging Satellite
4  April 2013. The 11th AD/PD Conference hosted a day-long exchange of new imaging data and discussion of current challenges for the research community in these two disorders...

  
Drug Data Dash at AAN Annual Conference
3  April 2013. There were so many new data on neurodegenerative disease trials at the recent AAN meeting that organizers crammed some of them into a session of three-minute talks...

  
From Natural History, A "Renaissance" for Amyloid Hypothesis
2  April 2013. Scientists quipped about Florence as a fitting setting for what they perceive to be a resurgence of the amyloid hypothesis after a beleaguered period of setbacks...

  
Sleep Patterns, Circadian Clock Linked to Aβ Oxidative Stress
2  April 2013. Disrupted sleep-wake cycles often accompany neurodegeneration, but scientists are unsure why...

  
Wrapping Up Enrollment, ADNI 2, PPMI Focus on Earlier Disease
2  April 2013. The Alzheimer’s Disease Neuroimaging Initiative steering committee gathered to exchange the latest developments in ADNI 2...

  
Anti-Amyloid Results Show Modest Benefits, Mild Side Effects
1  April 2013. Scientists continue to squeeze every last bit of information out of Phase 3 trials for anti-amyloid antibodies solanezumab and bapineuzumab...

  
In Pursuit of Toxic Tau
29  March 2013. Neurofibrillary tangles of tau protein litter Alzheimer’s disease brains, but are they actually bad for neurons?...

  
Quick-and-Early IVIG Therapy: Hints of Promise
29  March 2013. If another small, hopeful trial is to be believed, pooled antibody treatment has the potential to stave off dementia...

  
BACE Inhibitors Barrel Forward—Next Hurdles: Safety, Efficacy
28  March 2013. After more than a decade of seemingly pushing against a wall, BACE inhibitors for Alzheimer’s disease are finally surging forward...

  
Dementia in Movement Disorders: What Causes It?
27  March 2013. Adding insult to injury, many patients with a movement disorder get dementia, too...

  
Glial Imaging—Amid Slow Progress, EU Project Takes Up Challenge
26  March 2013. Calls for functional markers emanated loud and clear from the 3rd Venusberg Meeting on Neuroinflammation...

  
Taking Aim at M1: Old Hat or New Target?
26  March 2013. Some dismiss it as a therapeutic dead end, but for others, the M1 muscarinic receptor is a target for ongoing drug development research in Alzheimer’s disease...

  
Can Cancer Therapy Be Neurodegenerative Wonder Drug?
25  March 2013. A cancer drug newly proposed for neurodegenerative diseases seems to do it all...

  
LRRK Watchers’ Eyes Turn to Inflammation, Autophagy, Kinase
22  March 2013. With variants that boost risk for both familial and sporadic Parkinson’s disease, the LRRK2 gene beckons as a prime target for therapy development...

  
Blessing or Curse? Peripheral Cytokines in the Brain
22  March 2013. The subject of crosstalk between the peripheral circulation and the central nervous system permeated conversation...

  
Field Ramps Up "Mini" Mouse MRI
21  March 2013. As magnetic resonance imaging (MRI) resolution improves and more animal models become available, scientists are stepping up their use of mouse MRI...

  
Can Dousing PyroGlu-Aβ Treat Alzheimer’s Disease?
20  March 2013. Pyroglutamate Aβ is a particularly toxic version of the peptide at the center of AD pathogenesis; in fact, some scientists claim it seeds the formation of plaques...

  
1 to 25 of 780 results
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Brain on Fire
PIB PET in early AD patient reveals amyloid in cortex and deep brain areas.[Video courtesy of Scott Ziolko and the Pittsburgh Amyloid Imaging Group]
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