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Honolulu: Biomarker Profiles That Spell Trouble for ‘Normals’?
13  August 2010. Scientists have drafted a new set of diagnostic research criteria redefining AD as a condition that develops decades prior to obvious symptoms...

  
Honolulu: Monkey, Rat Join Menagerie of Mammalian AD Models
11  August 2010. Beyond the lab mouse, AD researchers may have access to a growing repertoire of brainier, brawnier species for their in vivo studies...

  
Honolulu: Neuroregeneration Taps Glia, Neurotrophins
4  August 2010. New data from several independent studies suggest using neural stem cells to patch wide swaths of failing brain circuitry in AD may have a fighting chance...

  
Noisy Response Greets Revised Diagnostic Criteria for AD
4  August 2010. Three groups presented results of their ongoing effort to incorporate scientific advances of the past quarter-century into a revision of the current diagnostic AD criteria...

  
Revised Criteria for Preclinical AD, Exactly as Presented
4  August 2010. Three workgroups of clinicians from the U.S. and Europe offered new guidelines for the diagnosis of AD...

  
What Do Clinicians Say? Peers Welcome Revised Criteria
4  August 2010. A comprehensive proposal of new diagnostic criteria marked a highlight at the International Conference on Alzheimer’s Disease...

  
Honolulu: TDP-43 Gets a Place in the Sun
31  July 2010. TDP-43 was an unknown in the neurodegeneration field until four years ago, but since then has received plenty of attention...

  
Honolulu: Intranasal Insulin Trial Claims Promise in MCI, AD
30  July 2010. Intranasal insulin seemed to improve certain measures of cognition and daily function, as well as biomarker profiles, in patients with MCI or early AD...

  
Honolulu: The Missing Link? Tau Mediates Aβ Toxicity at Synapse
26  July 2010. For the first time, a paper details a molecular mechanism that links tau to Aβ toxicity at the synapse...

  
Honolulu: Wake-Up Call—Aβ Clearance, Not Production, Awry in AD
26  July 2010. If β amyloid is indeed an early driver of Alzheimer disease pathogenesis, AD patients presumably churn out the peptide too quickly, clear it too slowly, or both...

  
Honolulu: Tomm40 Reported to Track With Brain Atrophy, Cognition
23  July 2010. Tomm40 has created a stir in AD research with the recent proposal that length of polymorphisms of this gene can help predict at what age a person may develop late-onset AD...

  
Honolulu: TrialMatch Launched as AD Is Becoming “Desktop” Disease
23  July 2010. AD diagnosis is moving from the bedside to the desktop, suggests Jason Karlawish...

  
Honolulu: FDA Approval in Sight for 18F Amyloid Tracer Florbetapir?
13  July 2010. Regulatory approval could be on the horizon for an amyloid tracer being developed for brain imaging using positron emission tomography (PET)...

  
DIAN Dispatch from Hawaii: Glimpse at Data, Push for Trials
13  July 2010. Leaders of DIAN gathered to brief each other to present to some 30 pharmaceutical industry scientists the first cut of baseline data from this ongoing biomarker study...

  
DIAN Dispatch From Hawaii: After Slow Start, Network Is Humming
12  July 2010. After more than a year of rumbling to life, the Dominantly Inherited Alzheimer’s Network (DIAN) has kicked into gear and is now enrolling research participants at a healthy clip...

  
St. Louis: ApoE—A Clearer View of its Role In AD?
5  July 2010. ApoE receptors enable a flurry of activity, much of it totally independent of amyloid-β pathology...

  
St. Louis: ApoE—Receptors, Theories and Therapies
2  July 2010. ApoE stands out for a frustrating mark of distinction...

  
St. Louis: ApoE Receptors—Hold Sway Over Synaptic Function
30  June 2010. The apolipoprotein E gene is the strongest genetic risk factor for late-onset Alzheimer disease...

  
Bethesda: "Ome" Sweet "Ome"—Epigenome Joins Genome, Proteome
28  June 2010. Histone acetylation is a particularly intriguing epigenetic mark, in part because it changes dynamically...

  
Bethesda: The Methylated Brain
25  June 2010. Methylation patterns being strongly influenced by the genetic makeup of the individual was taken up at the workshop...

  
Bethesda: Dawn of the Epigenetics Era
24  June 2010. Epigenetics, the study of how modifications to DNA and chromatin regulate the activity of genes, is the hot new thing in bioscience...

  
Toronto: HAI Amyloid Imaging Conference Abstracts
11  May 2010. Here we list the 39 abstracts presented at the Human Amyloid Imaging Conference held 9 April 2010 in Toronto, Canada...

  
Geneva: The AstraZeneca Ligand—The Fairest of Them All?
10  May 2010. This story ends with a glimpse of the newest kid on the block—18F AZD4694...

  
NIH Calls for More (and Different) Research on Preventive Measures
7  May 2010. A much greater investment in AD research will be needed before scientists can draw reliable conclusions about what factors increase or decrease risk of developing AD...

  
Toronto: Sister 18F Ligands Jostle for Primacy
7  May 2010. At the 4th Human Amyloid Imaging Conference, one 18F amyloid ligand strutted its Phase 3 stuff, while two others flaunted Phase 2 results...

  
1 to 25 of 532 results
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