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1 to 25 of 3360 results

Could Longevity Factor, Epilepsy Med, Treat AD One Day?
14 May 2013. At a San Francisco conference addressing Alzheimer’s and related disorders, the agenda featured a diverse mix of topics—occasionally even from the same lab...

Paracrine Signal From BACE1-Clipped Neuregulin Rescues Myelin
13 May 2013. As β-secretase inhibitors head into Alzheimer’s disease trials, researchers are paying close attention to what else BACE1 does besides snip amyloid-β from APP...

Endocytosis Pulls α-Secretase From Synapses
13 May 2013. Scientists report that endocytosis whisks α-secretase away from the cell membrane in a process that seems regulated by neuronal activity...

Guidelines at Nature Aim to Stem Tide of Irreproducibility
10 May 2013. It has become a complaint heard all too often—much academic research cannot be reproduced...

Therapeutic Approaches Target Deubiquitinase, Protein Turnover
10 May 2013. This scientific meeting that drew some 150 researchers to San Francisco 15-17 April 2013 featured an unusually broad array of topics...

Paper Alert: Antisense Oligonucleotide Therapy Safe for ALS?
9 May 2013. An oligonucleotide designed to tamp down an enzyme that causes amyotrophic lateral sclerosis seems safe...

Gammagard™ Misses Endpoints in Phase 3 Trial
8 May 2013. Topline data yesterday showed that intravenous immunoglobulin (IVIG) therapy, known as Gammagard™, failed to meet primary endpoints of slowing cognitive and functional decline...

Criminal Minds: Explaining Lack of Empathy in Prison Psychopaths
8 May 2013. People with psychopathic tendencies—who may constitute upwards of 15 percent of prison populations—poorly activate parts of the brain responsible for empathy...

Stem Cells Treat Epileptic Symptoms in Mice
8 May 2013. Using stem cells to replace inhibitory neurons in the hippocampi of adult epileptic mice reduced hyperexcitability, seizures, and behavioral deficits...

Not Seeing Eye to Eye: Do Lenses Accumulate Aβ?
8 May 2013. What if you could diagnose Alzheimer’s disease at an early stage by examining a person’s eyes?...

Do Microglia in the Hypothalamus Drive Aging?
3 May 2013. Microglia have taken center stage in Alzheimer’s disease (AD) research recently...

Can Transferrin Antibodies Safely Open the Blood-Brain Barrier?
3 May 2013. For decades scientists have sought a way to sneak large drugs across the blood-brain barrier...

ALS in Han Chinese: Different Race, Different Genetics?
3 May 2013. Researchers using genomewide screens have identified two new loci for sporadic amyotrophic lateral sclerosis genes in the Han Chinese population...

Research Brief: New Mouse Line for Studying Upper Motor Neurons
3 May 2013. In the study of ALS, lower motor neurons in the spine have received the lion's share of attention—but now there is a tool to focus on the role of upper motor neurons in the cortex...

Foundation Offers $100,000 for Sex Differences in Alzheimer’s
30 April 2013. Why are women at greater risk for Alzheimer's disease?...

ApoE Does Not Bind Aβ, Competes for Clearance
29 April 2013. Rather than sequestering Aβ to prevent its clearance from the brain, ApoE may indirectly block the peptide’s path to breakdown...

Does Progranulin Play Both Sides in AD and FTD?
26 April 2013. Mutations that cause frontotemporal dementia may also predispose carriers to Alzheimer’s dementia...

Newborn Healers—Novel Astrocytes Repair Brain Injury
26 April 2013. When leaky blood vessels damage the brain, the organ’s stem cell niche dispatches a specialist crew of astrocytes to stop the bleeding...

Cholinergic Neurons From Stem Cells Rescue Mouse Memories
26 April 2013. A new recipe for cooking up cholinergic neurons from stem cells may help researchers study what goes wrong with these cells in Alzheimer’s disease...

Aβ Vaccine Leads to Safer Immune Response in Mice
25 April 2013. A newly developed active amyloid-β vaccine removes Aβ from mouse brains while reducing inflammation and improving cognition...

As DIAN’s Scope Widens, Funding Narrows
25 April 2013. Public funding is becoming so scarce that the DIAN researchers are increasingly asking industry to help...

Stem Cell Screen Points to ALS Disease Target
19 April 2013. Therapies for amyotrophic lateral sclerosis (ALS) have proven hard to develop, in part because of inadequate disease models...

Parkinson’s Gene Increases Risk of Dementia
19 April 2013. One of the top Parkinson’s disease risk genes, GBA1, appears to be an even bigger risk factor for the related synucleinopathy dementia with Lewy bodies...

Safe at 4 Grams? No ARIA at High Dose of Human Aβ Antibody
18 April 2013. Researchers showed new data on how a therapeutic Aβ antibody their company had licensed from the Swiss biotech Neurimmune was measuring up...

Lilly Buys Tau Tracers From Siemens
17 April 2013. Eli Lilly and Company announced today that it has acquired the tau PET tracer program developed by Siemens Medical Solutions USA, Inc....

1 to 25 of 3360 results

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Not Seeing Eye to Eye: Do Lenses Accumulate Aβ?

Gammagard™ Misses Endpoints in Phase 3 Trial

Guidelines at Nature Aim to Stem Tide of Irreproducibility

Paper Alert: Antisense Oligonucleotide Therapy Safe for ALS?

New Assays for Aβ Oligomers in CSF Claim Femtogram Sensitivity

Check out our upcoming Webinar: Can Network Analysis Identify Pathological Pathways in Alzheimer’s

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The ALS Forum is a web-based collaborative effort to bring together valuable ALS-related resources for use by researchers worldwide in both academia and industry-based settings.

PIB PET in early AD patient reveals amyloid in cortex and deep brain areas.[Video courtesy of Scott Ziolko and the Pittsburgh Amyloid Imaging Group]