Alzforum News The Alzheimer Research Forum, a dynamic online scientific knowledge base, reports on the latest Alzheimer's scientific research and develops databases of genes, scientific articles, animal models, antibodies, medications, grants, research jobs, and more. http://www.alzforum.org/ Copyright © 1996-2010 Alzheimer Research Forum en-us http://www.alzforum.org/images/header_1a.gif Alzheimer Research Forum http://www.alzforum.org/ 170 72 ALS—A Polyglutamine Disease? Mid-length Repeats Boost Risk Researchers have mediated a merger of sorts between two distinct neurodegenerative conditions—ALS and (SCA)—and the proteins that cause them... http://www.alzforum.org/new/detail.asp?id=2546 28 Aug 2010 00:00:00 EST Insulin Resistance Correlates With Plaque, But Not Tangle, Pathology Having diabetes seems to drive up risk for dementia, including Alzheimer disease, but the jury has been out as to how this occurs... http://www.alzforum.org/new/detail.asp?id=2545 28 Aug 2010 00:00:00 EST Common Ground: Is Aβ the Foundation for Multiple Dementias? The majority of patients with Parkinson disease eventually develop dementia, but what pathology underlies this decline?... http://www.alzforum.org/new/detail.asp?id=2544 27 Aug 2010 00:00:00 EST New Theory for Some ALS Cases—SOD1 Plugs Cell Power Plants The misfolded enzyme that causes some kinds of amyotrophic lateral sclerosis poisons motor neurons by plugging up pores in their mitochondria... http://www.alzforum.org/new/detail.asp?id=2543 27 Aug 2010 00:00:00 EST http://www.alzforum.org/new/detail.asp?id=2543#dispcomments Putting the Squeeze on Vascularization—A Link Between Cancer and Aβ? Several studies have shown that Alzheimer’s patients appear to be less susceptible to cancer, but the mechanism behind this association remains mysterious... http://www.alzforum.org/new/detail.asp?id=2542 27 Aug 2010 00:00:00 EST Off Key—Aβ Detunes the Theta Rhythms of the Hippocampus Surprisingly little is known about how AD affects the electrical activity of the hippocampus... http://www.alzforum.org/new/detail.asp?id=2541 25 Aug 2010 00:00:00 EST TDP-43 and Tau Entangle Athletes’ Nerves in Rare Motor Neuron Disease Getting hit in the head might not just ring your bell—in rare cases, it may predispose athletes in contact sports to motor neuron disease... http://www.alzforum.org/new/detail.asp?id=2540 25 Aug 2010 00:00:00 EST Another Step in the Protein Aggregation Recipe There is a new ingredient in the complex mix that yields masses of malformed proteins... http://www.alzforum.org/new/detail.asp?id=2539 22 Aug 2010 00:00:00 EST A Toll on Memory: New Role for Immune-Related Receptor in Brain Mounting evidence suggests that immune system molecules can wear different hats in the central nervous system... http://www.alzforum.org/new/detail.asp?id=2538 22 Aug 2010 00:00:00 EST Getting to First BACE: BACE1 Inhibition Takes a Step Forward Inhibition of the β-secretase enzyme has long been seen as one of the most promising therapeutic options for Alzheimer disease... http://www.alzforum.org/new/detail.asp?id=2537 20 Aug 2010 00:00:00 EST