Jobs

Postdoctoral Scientist in Neurodegeneration

Employer

University of Kentucky, Sanders-Brown Center on Aging

Location

Lexington, Kentucky

Principal Investigator

Linda Van Eldik

Contact

Applicants should send an email that includes a cover letter with a brief statement of research experience and career goals, a curriculum vitae, and names and contact information for three references to Dr. Linda Van Eldik.

Description

A postdoctoral scientist position is available immediately at the University of Kentucky, Lexington, in the Sanders-Brown Center on Aging. The successful candidate will benefit from an experienced mentor, a stimulating and collaborative research environment, and an organized training plan. Although the project is currently funded by NIH, an integral part of postdoctoral training is the process of preparing a research proposal and writing a fellowship application, so postdocs are encouraged to apply for external funding when possible. Recent postdocs in the lab have been successful at obtaining NIH-funded F32 and K99/R00 awards, which provide recognition for both the fellow and the Center on Aging.

The center seeks a highly motivated, creative, and collaborative individual to work on mechanistic and translational research projects focused on the detrimental inflammatory and neurodegenerative responses that contribute to pathophysiology in mouse models of CNS disorders, especially traumatic brain injury (TBI) and Alzheimer’s disease (AD). One project is defining the role of the stress-related kinase, p38α MAPK, in regulating the TBI-induced up-regulation of proinflammatory molecules that lead to disease-relevant neuropathology and behavioral impairments. Through the use of novel mouse models and CNS-penetrant experimental therapeutics, the center's researchers are defining when, where and how p38α MAPK can be targeted for beneficial outcomes.

Requirements

Ph.D. or M.D./Ph.D. in an area relevant to pharmacology or neuroscience. Must have excellent interpersonal, organizational, verbal and written communication skills, a solid publication record, and appropriate experience. Preference will be given to individuals with experience in one of the following areas: inducible conditional knockout mouse models, mouse neuropathology and behavior, primary glia/neuron cell culture, gene expression profiling, pharmacological modulation of glia signaling pathways.

Prior experience in AD, TBI, or related neurological disease research is also desirable.