Postdoctoral Research Associate


University of Cambridge


Cambridge, England, United Kingdom

Principal Investigator

William McEwan


Please contact Heather Carlyon with questions about the vacancy or the application process.

Informal enquiries can be directed to Will McEwan.


An opportunity has arisen to join the Cytosolic Protein Targeting Group at the U.K. Dementia Research Institute, hosted in the Department of Clinical Neurosciences at the University of Cambridge. This group is headed by Will McEwan and investigates cellular mechanisms that can bring about the selective degradation of pathogenic proteins in the cytosol. A major goal is in using intracellular immunity to selectively target assemblies of tau, a protein that aggregates during Alzheimer's disease.

This position is aimed at investigating the ability of misfolded proteins to propagate in cell-based and in vitro systems. It is funded by IMPRiND, an international consortium that seeks novel therapeutic approaches in Alzheimer's and Parkinson's diseases. The position therefore represents an opportunity to work alongside many of the leading academic and industry groups in the field in a highly collaborative manner.

The funds for this post are available for two years in the first instance.

For instructions on how to apply, please follow this link:

Closing date: August 27, 2017.


The post-holder must hold a Ph.D. or equivalent (or be in the course of finishing a Ph.D.). A variety of techniques will be employed during the course of the research, likely including mammalian cell culture, recombinant protein production, biophysical techniques, and various light and electron microscopy techniques. Experience in several of these is highly advantageous. Experience in the fields of neurobiology or protein misfolding is desirable though candidates with any relevant background will be considered.