Postdoctoral Fellowship Studying the Activity of Human Brain-Derived Aβ


Brigham and Women's Hospital / Harvard Medical School


Boston, Massachusetts, U.S.A.


Expressions of interest should be directed to Dominic Walsh (


Working jointly in the laboratories of Dominic Walsh and Dennis Selkoe at the Center for Neurologic Diseases, Brigham and Women's Hospital and Harvard Medical School, the successful applicant will become a key member of a small, focused team that will include a full-time research assistant and an electrophysiologist working on purifying and testing the activity of water-soluble Aβ species isolated from human brain.  The project will be labor-intensive and it is important that we appoint a highly motivated candidate with an excellent work ethic and an eye for detail.

Applicants should have substantial hands-on experience in protein biochemistry, including chromatographic techniques used for purification and analysis. Applicants should also have extensive experience using immunological techniques such as ELISA, immunopreciptation and Western blotting. It would also be advantageous to be competent in the preparation of rat hippocampal cultures.

The position will be available from March 1, 2014.


The successful applicant will be exposed to a wide range of additional techniques and will interact on a daily basis with the PIs and a diverse and active group of molecular scientists interested in neurodegeneration.