Neuroscience Biomarkers Scientist
Posted 31 Jul 2013
Janssen Research & Development, L.L.C.
Raritan, New Jersey, U.S.A.
As a valued team member, you'll receive a competitive salary and great benefits including medical/dental, a 401(k), a pension plan, and a comprehensive wellness program. If interested, please apply online. The Johnson & Johnson Family of Companies has a strong commitment to diversity and welcomes applications for all individuals. EOE M/F/D/V
The scientist will be someone who can approach the challenge of discovering and developing biomarker strategies and measurements in support of pre-clinical and clinical studies for Alzheimer's disease and mood disorders. This position has a focus on both supervision of laboratory personnel and personal research responsibilities in the biomarker pilot laboratory.
The neuroscience biomarker scientist will be a member of the neuroscience biomarkers team, and will be responsible for evaluating potential biomarkers for their application in clinical trials and as diagnostics. This position will participate in creating and executing biomarker strategies for therapies under development for the treatment of neurologic and psychiatric disorders and pain. He or she will also direct activities related to the validation and qualification of biomarkers to be developed as assays for clinical studies or diagnostics.
This position will be expected to interface and collaborate with academia, pre-competitive industrial consortia (such as ADNI, BIRN, FNIH, etc.), and commercial vendors to ensure optimal support of neuroscience biomarker and diagnostic capabilities. The neuroscience biomarker expert will also interface with internal and external experts in pharmacogenomics, proteomics, transcriptomics, metabalomics, neuroimaging, and other biomarker platforms to contribute to multimodal biomarker strategies.
The successful candidate will be expected to track the evolving landscape of neurologic and neuropsychiatric disease biomarker technology—including cutting-edge research in academic labs, potentially competitive capabilities in start-up ventures, and the various R&D pipelines of the major biotechnology vendors.
Collaboration with preclinical scientists and clinical experts will also be expected.
- A minimum of a Ph.D. or M.D./D.O., with experience in neuroscience is required.
- At least two years of postdoctoral studies using protein biochemical strategies to study problems of the nervous system is required.
- An understanding of techniques, including mass spectrometry, protein and peptide separations, protein electrophoretic techniques, use of immunoassays, characterization of antibodies for assay building, and cell signaling is preferred.
- Publications that demonstrate the relevant understanding are preferred.
- Training and experience in biomarker discovery, and application to drug development are preferred.
- A strong understanding of the drug development and clinical trials process in the pharmaceutical industry, based on experience in pharmaceutical/biotech company, is preferred.
- A proven track record of research in relation to compounds for neuroscience indications and of execution and delivery against strategic goals is preferred.
- Specific experience and insights into how biomarker platforms and technologies can be integrated to provide practical solutions of clinical utility are preferred.