Associate Researcher, AD
Posted 22 Apr 2014
Institute for Memory Impairments and Neurological Disorders, University of California, Irvine
Irvine, California, U.S.A.
Please submit a letter of interest, C.V. which should include a record of research experience and the names of three references before May 1, 2014 to:
Dr. Frank LaFerla/Andrea Wasserman
Institute for Memory Impairments and Neurological Disorders
2642 Biological Sciences III
Irvine, CA 92697-4550
The Institute for Memory Impairments and Neurological Disorders (UCI MIND) is seeking a highly motivated individual who has extensive experience working in the area of pharmacology and immunology of neuronal degeneration using animal models and cell culture systems to advance our understanding of Alzheimer disease (AD). The professional researcher series at UCI is designed for scientists who engage in independent and creative high quality research. Applicants should have a proven track record of consistent publications in this area and independent funding.
The candidate will lead projects evaluating novel immune-based targets for AD. Projects will focus on aspects of innate and adaptive immune systems, learning and memory, synaptic function and plasticity, lipid metabolism, proteomic and metabolomics discovery, and endocytic dysfunction. Additionally, we seek a candidate with adeno-associated virus (AAV)-based research experience, in both in vivo and in vitro systems. Experience in animal models of AD is required, particularly knowledge of animal surgeries and behavior. Also, experience studying both amyloid and tau neuropathology is a plus. The candidate should have some familiarity, and ideally hands-on experience, with state-of-the-art techniques of microscopy (stereology and confocal), meso-scale discovery, nanostring, and biacore. The ideal candidate should have a strong background in pharmacology, immunology and molecular biology. The candidate will be responsible for experimental design, data analyses, and manuscript preparation. The candidate will also be expected to apply for both independent and collaborative funding to support his/her research focus.
A Ph.D. in pharmacology or immunology with 6-plus years of postdoctoral scientific experience in neurobiology, neuropathology, and neurodegenerative diseases; a demonstrated record of innovative research with strong publications, excellent training, and clear scientific contributions. At least 10 years of experience working with rodent models and animal behavior is required. Candidates must be able to work effectively with interdisciplinary teams and to manage scientific projects within a complex organization; excellent interpersonal, organizational, and oral and written communication skills are essential. This position will be appointed at the level that is commensurate with the education and experience of the individual candidate.