Updated 26 November 2007

Diagnosis
Diagnosis of Early-onset Alzheimer Disease
Sidebar: Pushing the Envelope on Early Diagnosis
Interview: A Diagnostic Odyssey

Genetics
Genetic Testing and Counseling for Early-onset Familial AD
Sidebar: The Specter of Suicide
Sidebar: Taking the Plunge into Genetic Testing
Interview with Jennifer Williamson
Interview: One Man's Forward Approach
Protocol for Predictive Testing

Our Diagnosis and Genetics section provides information on the kinds of procedures to expect in a diagnosis of early-onset familial Alzheimer disease (eFAD). The disease is often missed or misdiagnosed; we will tell the story of one couple's experience. While genetic testing is becoming an increasingly important part of the diagnostic process, it is fraught with risks and implications for the entire family that need to be carefully considered. We present pros and cons of the different kinds of genetic testing available. In addition, we present profiles with people who have opted for or against predictive testing, a cautionary interview with a genetic counselor, as well as a blueprint of an appropriate genetic counseling protocol that interested candidates should expect as they consider whether to take this step.