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Gordon Research Conference: Biology of Aging

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Les Diablerets, Switzerland
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The 2017 Gordon Research Conference (GRC) on the Biology of Aging will be held at the Les Diablerets Conference Center, immediately after the Gordon Research Seminar (GRS), which will be held at the same location on July 8-9. The program has been developed around the theme of "Integrative Biology of Aging: New Insights from Molecules to Systems". Recent studies from diverse model organisms have demonstrated that systemic interplay between multiple tissues and organs regulates aging and longevity. Additionally, subcellular systems such as organelles and stress pathways can often communicate intra- and intercellularly. To dissect such complex systemic regulation of aging and longevity, significant progress has been made in identifying control networks and basic architectures, but how communication is achieved at different levels of organization and assembled into larger architectures is only beginning to be explored. The dysfunction of critical components in these control networks contributes to the induction of the cellular and molecular hallmarks of aging, including mitochondrial dysfunction, epigenetic alterations, chronic inflammation, circadian rhythm dysfunction, genomic instability, loss of proteostasis, and others, and underlies diminished healthspan and lifespan. The major objective of the conference and seminar is to capture this new wave of the "integrative biology of aging", and stimulate thought and effort to translate knowledge into effective interventions to achieve "productive aging."