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Researcher Profile - Dezhi Liao Get Newsletter
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Home: Community: Researcher Profiles
Researcher Profile

RESEARCHER INFORMATION
First Name:Dezhi
Last Name:Liao
Title:Associate Professor
Advanced Degrees:Ph.D.
Affiliation:The University of Minnesota
Department:Neuroscience
Street Address 1:Rm 6-145 Jackson Hall
Street Address 2:321 Church St
City:Minneapolis
State/Province:MN
Zip/Postal Code:55455
Country/Territory:U.S.A.
Phone:612 626 3522
Fax:612 626 5009
Email Address: 
Disclosure:
(view policy) 
Member reports no financial or other potential conflicts of interest. [Last Modified: 20 December 2010]
View all comments by Dezhi Liao
Clinical Interests:
Tauopathies, Alzheimer Disease
Research Focus:
Tau/Cytoskeleton, A-beta PP/A-beta, Neurobiology
Work Sector(s):
University
Web Sites:
Professional: www.umn.com
Researcher Bio
2007-present The University of Minnesota: (Neuroscience) Associate Professor
2000 - 2007 The University of Minnesota: (Neuroscience) Assistant Professor
1996 - 2000 The Johns Hopkins University: (Neuroscience) Postdoctoral Fellow
1994 - 1996 Cold Spring Harbor Laboratory, New York: (Neuroscience) Graduate Research Assistant
1991 - 1996 The University of Iowa: (Neuroscience) Graduate Research Assistant
Top Papers
1. Angel Y.F. Kam, Dezhi Liao, Horace H. Loh and Ping-Yee Law (2010). Morphine induces AMPA receptor internalization via calcineurin-dependent dephosphorylation of GluR1 subunit. Journal of Neuroscience, in press.

2. Hoover BR, Reed MN, Su J, Penrod RD, Kotilinek LA, Grant MK, Pitstick R, Carlson GA, Lanier LM, Yuan LL, Ashe KH, Liao D (2010). Tau mislocalization to dendritic spines mediates synaptic dysfunction independently of neurodegeneration. Neuron, in press.

3. Lin, H., Higgins, P., Loh, Horace, Law, P-Y, Liao, D. (2009). Bidirectional effects of fentanyl on dendritic spines and AMPA receptors depend upon the internalization of mu opioid receptors. Neuropsychopharmacology, 34(9):2097-111.

4. Wiens, K., Lin, H. and Liao, D. (2005). Rac1 induces the clustering of AMPA receptors during spinogenesis. J. Neurosci. 25, 10627-10636.

5. Liao D., Lin, H., P-Y Law, H.H. Loh (2005). Mu opioid receptors modulate the stability of dendritic spines. Proc Natl Acad Sci U S A. 102, 1725-1730.

6. Liao, D., Hessler, N. A. and Malinow, R. (1995). Activation of postsynaptically silent synapses during pairing-induced LTP in CA1 region of hippocampal slice. Nature, 375:400-404.

7. Liao, D., Jones, A. and Malinow, R. (1992). Direct measurement of quantal changes underlying long-term potentiation in CA1 hippocampus. Neuron, 9:1089-1097.

8. Liao, D., Zhang, X., O Brien, R., Ehlers, M. D., and Huganir, R. L. (1999). Regulation of morphological postsynaptic silent synapses in developing hippocampal neurons. Nature Neuroscience 2:37-43.

9. Liao, D., Grigoriants, O.O., Wang, W., Wiens, K., Loh, H.H. and Law, P.Y. (2007) Distinct effects of individual opioids on the morphology of spines depend upon the internalization of mu opioid receptors. Mol Cell Neurosci. 35, 456-469.

10. Liao, D., Grigoriants, O.O., Loh, H.H. and Law, P.Y. (2007). Agonist-dependent postsynaptic effects of opioids on miniature excitatory postsynaptic currents in cultured hippocampal neurons. J Neurophysiol. 97(2):1485-1494.

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